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MIRAGE
Fc gamma receptor IIIb
Summary
- Gene Symbol
-
- FCGR3B
- Aliases
-
- CD16
- CD16b
- FcRIIIb
- FcgammaRIIIb
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Disulfide bond
- GPI-anchor
- IgG-binding protein
- Immunoglobulin domain
- Proteomics identification
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| O75015 |
|
| A0A3B3ISU3 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| antibody-dependent cellular cytotoxicity | ||
| immune response | ||
| cell surface receptor signaling pathway | ||
| Fc-gamma receptor signaling pathway |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| plasma membrane | ||
| plasma membrane | ||
| external side of plasma membrane | ||
| secretory granule membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| IgG receptor activity | ||
| IgG binding | ||
| GPI anchor binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- low affinity immunoglobulin gamma Fc region receptor III
- Functional Category
-
- G: Carbohydrate transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| cell surface receptor signaling pathway |
| InterPro |
|---|
| Immunoglobulin-like domain |
KEGG BRITE Database
Disease
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000093 | Proteinuria |
| HP:0000155 | Oral ulcer |
| HP:0000488 | Retinopathy |
| HP:0000716 | Depression |
| HP:0000790 | Hematuria |
| HP:0000822 | Hypertension |
| HP:0000952 | Jaundice |
| HP:0000992 | Cutaneous photosensitivity |
| HP:0001250 | Seizure |
| HP:0001287 | Meningitis |
| Disease ID | Disease Name |
|---|---|
| ORPHA:464370 |
|
| ORPHA:536 |
|
PubChem Disease
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 2205 | Xenbase:XB-GENE-941359 | ||
| 2209 | Xenbase:XB-GENE-5962076 | ||
| 2212 | Xenbase:XB-GENE-941359 | ||
| 2213 | Xenbase:XB-GENE-941359 | ||
| 2214 | Xenbase:XB-GENE-5962076 | ||
| 2215 | Xenbase:XB-GENE-941359 | ||
| 9103 | Xenbase:XB-GENE-941359 | ||
| 14125 | Xenbase:XB-GENE-941359 | ||
| 14129 | Xenbase:XB-GENE-5962076 | ||
| 14130 | Xenbase:XB-GENE-941359 |
