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Fc gamma receptor IIIb
Summary
- Gene Symbol
-
- FCGR3B
- Aliases
-
- CD16
- CD16b
- FcRIIIb
- FcgammaRIIIb
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Disulfide bond
- GPI-anchor
- IgG-binding protein
- Immunoglobulin domain
- Proteomics identification
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| O75015 |
|
| A0A3B3ISU3 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| antibody-dependent cellular cytotoxicity | ||
| immune response |
|
|
| Fc-gamma receptor signaling pathway | ||
| cell surface receptor signaling pathway |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| external side of plasma membrane | ||
| plasma membrane | ||
| secretory granule membrane |
|
|
| extracellular exosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| GPI anchor binding | ||
| IgG binding | ||
| IgG receptor activity |
GO Hierarchy
KEGG BRITE Database
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0040085 | bacterial sepsis | |
| DOID:0050156 | idiopathic pulmonary fibrosis | |
| DOID:0050167 | autoimmune polyendocrine syndrome type 1 | |
| DOID:0050387 | nonpapillary renal cell carcinoma | |
| DOID:0050458 | juvenile myelomonocytic leukemia | |
| DOID:0050523 | adult T-cell leukemia/lymphoma | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050590 | severe congenital neutropenia | |
| DOID:0050646 | distal arthrogryposis | |
| DOID:0050745 | diffuse large B-cell lymphoma |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0002090 | Pneumonia |
| HP:0002716 | Lymphadenopathy |
| HP:0003453 | Antineutrophil antibody positivity |
| HP:0003493 | Antinuclear antibody positivity |
| HP:0005268 | Miscarriage |
| HP:0005421 | Decreased circulating complement C3 concentration |
| HP:0005968 | Temperature instability |
| HP:0007417 | Discoid lupus rash |
| HP:0009800 | Maternal diabetes |
| HP:0012085 | Pyuria |
| Disease ID | Disease Name |
|---|---|
| ORPHA:464370 |
|
| ORPHA:536 |
|
PubChem Disease
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 496987 | Xenbase:XB-GENE-5844396 | ||
| 734130 | Xenbase:XB-GENE-5962076 | ||
| 100486925 | Xenbase:XB-GENE-941359 | ||
| 100491172 | Xenbase:XB-GENE-5960290 | ||
| 100387926 | CALJA16109 | ||
| 720006 | MACMU24080 | ||
| 745350 | PANTR49310 | ||
| 100453994 | PONAB18212 | ||
| 478984 | CANLF14400 | ||
| 100481923 | AILME11914 |
