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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fc gamma receptor IIIb
Summary
- Gene Symbol
-
- FCGR3B
- Aliases
-
- CD16
- CD16b
- FcRIIIb
- FcgammaRIIIb
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Disulfide bond
- GPI-anchor
- IgG-binding protein
- Immunoglobulin domain
- Proteomics identification
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| O75015 |
|
| A0A3B3ISU3 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| antibody-dependent cellular cytotoxicity | ||
| immune response |
|
|
| Fc-gamma receptor signaling pathway | ||
| cell surface receptor signaling pathway |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| external side of plasma membrane | ||
| plasma membrane | ||
| secretory granule membrane |
|
|
| extracellular exosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| GPI anchor binding | ||
| IgG binding | ||
| IgG receptor activity |
GO Hierarchy
KEGG BRITE Database
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080199 | colorectal carcinoma | |
| DOID:0080334 | aortic valve disease 2 | |
| DOID:0080348 | Alzheimer's disease 1 | |
| DOID:0080379 | nephrotic syndrome type 2 | |
| DOID:0090018 | autosomal dominant familial periodic fever | |
| DOID:0090029 | CINCA Syndrome | |
| DOID:0090103 | Huntington's disease-like 1 | |
| DOID:0090104 | Huntington's disease-like 2 | |
| DOID:0110035 | Alzheimer's disease 2 | |
| DOID:0110037 | Alzheimer's disease 5 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000093 | Proteinuria |
| HP:0000155 | Oral ulcer |
| HP:0000488 | Retinopathy |
| HP:0000716 | Depression |
| HP:0000790 | Hematuria |
| HP:0000822 | Hypertension |
| HP:0000952 | Jaundice |
| HP:0000992 | Cutaneous photosensitivity |
| HP:0001250 | Seizure |
| HP:0001287 | Meningitis |
| Disease ID | Disease Name |
|---|---|
| ORPHA:464370 |
|
| ORPHA:536 |
|
PubChem Disease
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 496987 | Xenbase:XB-GENE-5844396 | ||
| 734130 | Xenbase:XB-GENE-5962076 | ||
| 100486925 | Xenbase:XB-GENE-941359 | ||
| 100491172 | Xenbase:XB-GENE-5960290 | ||
| 100387926 | CALJA16109 | ||
| 720006 | MACMU24080 | ||
| 745350 | PANTR49310 | ||
| 100453994 | PONAB18212 | ||
| 478984 | CANLF14400 | ||
| 100481923 | AILME11914 |
