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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fc gamma receptor IIIb
Summary
- Gene Symbol
-
- FCGR3B
- Aliases
-
- CD16
- CD16b
- FcRIIIb
- FcgammaRIIIb
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Disulfide bond
- GPI-anchor
- IgG-binding protein
- Immunoglobulin domain
- Proteomics identification
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| O75015 |
|
| A0A3B3ISU3 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| Fc-gamma receptor signaling pathway | ||
| cell surface receptor signaling pathway | ||
| immune response | ||
| antibody-dependent cellular cytotoxicity |
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| secretory granule membrane | ||
| plasma membrane | ||
| extracellular region | ||
| extracellular exosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| IgG receptor activity | ||
| IgG binding | ||
| GPI anchor binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Immunoglobulin
- Functional Category
-
- G: Carbohydrate transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| cell surface receptor signaling pathway |
| InterPro |
|---|
| Immunoglobulin subtype |
| Immunoglobulin-like domain superfamily |
| Immunoglobulin-like domain |
| Immunoglobulin-like fold |
KEGG BRITE Database
Disease
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0002090 | Pneumonia |
| HP:0002716 | Lymphadenopathy |
| HP:0003453 | Antineutrophil antibody positivity |
| HP:0003493 | Antinuclear antibody positivity |
| HP:0005268 | Miscarriage |
| HP:0005421 | Decreased circulating complement C3 concentration |
| HP:0005968 | Temperature instability |
| HP:0007417 | Discoid lupus rash |
| HP:0009800 | Maternal diabetes |
| HP:0012085 | Pyuria |
| Disease ID | Disease Name |
|---|---|
| ORPHA:536 |
|
| ORPHA:464370 |
|
PubChem Disease
- KEGG Diseases
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 113883690 | BOBOX06713 | |||
| 129036148 | 9600_0:000704 | |||
| 129397763 | 9597_0:000107 |
