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unc-13 homolog A

Summary

Gene Symbol

UNC13A

Organism

Homo sapiens (human)

External Links

NCBI Gene

23025

PubChem

23025

Alliance of Genome Resources

HGNC:23150

JoGo

UNC13A

TogoVar

UNC13A

Annotation

Keyword

Calcium
Cell membrane
Cell projection
Coiled coil
Cytoplasm
Differentiation
Exocytosis
Membrane
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Synapse
Zinc-finger

Proteins

Displaying **all 2** entries
UniProt	Protein Name
F8VZH8
Q9UPW8	Munc13-1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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2

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GO Term	Evidence Code	PMID
neurotransmitter secretion	ISS
synaptic vesicle docking	IBA
synaptic vesicle priming	IBA
cell differentiation	IEA
synaptic transmission, glutamatergic	IBA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

calcium-ion regulated exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

vesicle-mediated transport in synapse [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

membrane docking [inference]

organelle localization by membrane tethering [inference]

vesicle docking [inference]

vesicle docking involved in exocytosis [inference]

synaptic vesicle docking

cellular developmental process [inference]

cell differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

exocytic process [inference]

vesicle docking involved in exocytosis [inference]

synaptic vesicle docking

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

calcium-ion regulated exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

developmental process [inference]

cellular developmental process [inference]

cell differentiation

localization [inference]

establishment of localization [inference]

transport [inference]

neurotransmitter transport [inference]

neurotransmitter secretion

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

calcium-ion regulated exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

vesicle-mediated transport in synapse [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

secretion [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

calcium-ion regulated exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

calcium-ion regulated exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

establishment of localization in cell [inference]

neurotransmitter secretion

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

establishment of vesicle localization [inference]

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

organelle localization [inference]

vesicle localization [inference]

secretory granule localization [inference]

dense core granule localization [inference]

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

establishment of vesicle localization [inference]

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

organelle localization by membrane tethering [inference]

vesicle docking [inference]

vesicle docking involved in exocytosis [inference]

synaptic vesicle docking

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, glutamatergic

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

regulation of growth [inference]

regulation of cell growth [inference]

positive regulation of cell growth [inference]

positive regulation of dendrite extension

regulation of dendrite extension [inference]

positive regulation of dendrite extension

positive regulation of growth [inference]

positive regulation of cell growth [inference]

positive regulation of dendrite extension

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

regulation of developmental growth [inference]

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

regulation of dendrite extension [inference]

positive regulation of dendrite extension

positive regulation of biological process [inference]

positive regulation of growth [inference]

positive regulation of cell growth [inference]

positive regulation of dendrite extension

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

positive regulation of cellular process [inference]

positive regulation of cell growth [inference]

positive regulation of dendrite extension

positive regulation of developmental process [inference]

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of dendrite extension [inference]

positive regulation of dendrite extension

regulation of developmental growth [inference]

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

regulation of dendrite extension [inference]

positive regulation of dendrite extension

positive regulation of developmental process [inference]

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, glutamatergic

positive regulation of cellular process [inference]

positive regulation of cell growth [inference]

positive regulation of dendrite extension

regulation of cellular component organization [inference]

regulation of cell growth [inference]

positive regulation of cell growth [inference]

positive regulation of dendrite extension

regulation of dendrite extension [inference]

positive regulation of dendrite extension

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
plasma membrane	IBA
synaptic vesicle membrane	IBA
neuromuscular junction	IBA
presynaptic membrane	ISS
presynaptic membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm [inference]

cell cortex [inference]

cell cortex region [inference]

presynaptic active zone cytoplasmic component

cytoplasmic region [inference]

cell cortex region [inference]

presynaptic active zone cytoplasmic component

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic membrane

cell junction [inference]

synapse [inference]

neuromuscular junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

presynaptic active zone

presynapse [inference]

terminal bouton

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
calcium ion binding	IEA
calmodulin binding	ISS
calmodulin binding	IBA
phospholipid binding	IEA
zinc ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

SNARE binding [inference]

syntaxin binding [inference]

syntaxin-1 binding

calmodulin binding

lipid binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:332	amyotrophic lateral sclerosis	Alliance of Genome Resources

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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