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unc-13 homolog A

Summary

Gene Symbol

UNC13A

Organism

Homo sapiens (human)

External Links

NCBI Gene

23025

PubChem

23025

Alliance of Genome Resources

HGNC:23150

JoGo

UNC13A

TogoVar

UNC13A

Annotation

Keyword

Calcium
Cell membrane
Cell projection
Coiled coil
Cytoplasm
Differentiation
Exocytosis
Membrane
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Synapse
Zinc-finger

Proteins

Displaying **all 2** entries
UniProt	Protein Name
F8VZH8
Q9UPW8	Munc13-1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 10 in total

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GO Term	Evidence Code	PMID
regulation of synaptic transmission, glutamatergic	TAS	15217342
dense core granule priming	IBA
neuronal dense core vesicle exocytosis	ISS
presynaptic dense core vesicle exocytosis
positive regulation of dendrite extension	IDA	23999003

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

calcium-ion regulated exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

vesicle-mediated transport in synapse [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

membrane docking [inference]

organelle localization by membrane tethering [inference]

vesicle docking [inference]

vesicle docking involved in exocytosis [inference]

synaptic vesicle docking

cellular developmental process [inference]

cell differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

exocytic process [inference]

vesicle docking involved in exocytosis [inference]

synaptic vesicle docking

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

calcium-ion regulated exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

developmental process [inference]

cellular developmental process [inference]

cell differentiation

localization [inference]

establishment of localization [inference]

transport [inference]

neurotransmitter transport [inference]

neurotransmitter secretion

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

calcium-ion regulated exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

vesicle-mediated transport in synapse [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

secretion [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

calcium-ion regulated exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

calcium-ion regulated exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

establishment of localization in cell [inference]

neurotransmitter secretion

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter [inference]

presynaptic dense core vesicle exocytosis

establishment of vesicle localization [inference]

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

organelle localization [inference]

vesicle localization [inference]

secretory granule localization [inference]

dense core granule localization [inference]

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

establishment of vesicle localization [inference]

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

dense core granule exocytosis [inference]

neuronal dense core vesicle exocytosis

presynaptic dense core vesicle exocytosis

organelle localization by membrane tethering [inference]

vesicle docking [inference]

vesicle docking involved in exocytosis [inference]

synaptic vesicle docking

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, glutamatergic

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

regulation of growth [inference]

regulation of cell growth [inference]

positive regulation of cell growth [inference]

positive regulation of dendrite extension

regulation of dendrite extension [inference]

positive regulation of dendrite extension

positive regulation of growth [inference]

positive regulation of cell growth [inference]

positive regulation of dendrite extension

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

regulation of developmental growth [inference]

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

regulation of dendrite extension [inference]

positive regulation of dendrite extension

positive regulation of biological process [inference]

positive regulation of growth [inference]

positive regulation of cell growth [inference]

positive regulation of dendrite extension

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

positive regulation of cellular process [inference]

positive regulation of cell growth [inference]

positive regulation of dendrite extension

positive regulation of developmental process [inference]

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of dendrite extension [inference]

positive regulation of dendrite extension

regulation of developmental growth [inference]

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

regulation of dendrite extension [inference]

positive regulation of dendrite extension

positive regulation of developmental process [inference]

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, glutamatergic

positive regulation of cellular process [inference]

positive regulation of cell growth [inference]

positive regulation of dendrite extension

regulation of cellular component organization [inference]

regulation of cell growth [inference]

positive regulation of cell growth [inference]

positive regulation of dendrite extension

regulation of dendrite extension [inference]

positive regulation of dendrite extension

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
plasma membrane	IBA
synaptic vesicle membrane	IBA
neuromuscular junction	IBA
presynaptic membrane	ISS
presynaptic membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm [inference]

cell cortex [inference]

cell cortex region [inference]

presynaptic active zone cytoplasmic component

cytoplasmic region [inference]

cell cortex region [inference]

presynaptic active zone cytoplasmic component

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic membrane

cell junction [inference]

synapse [inference]

neuromuscular junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

presynaptic active zone

presynapse [inference]

terminal bouton

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
calcium ion binding	IEA
calmodulin binding	ISS
calmodulin binding	IBA
phospholipid binding	IEA
zinc ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

SNARE binding [inference]

syntaxin binding [inference]

syntaxin-1 binding

calmodulin binding

lipid binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:332	amyotrophic lateral sclerosis	Alliance of Genome Resources

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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