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Guidelines

MIRAGE

kinesin family member 21B

Summary

Gene Symbol

KIF21B

Organism

Homo sapiens (human)

External Links

NCBI Gene

23046

PubChem

23046

Alliance of Genome Resources

HGNC:29442

Annotation

Keyword

ATP-binding
Alternative splicing
Cell projection
Coiled coil
Cytoplasmic vesicle
Cytoskeleton
Microtubule
Motor protein
Phosphoprotein
Reference proteome
Repeat
WD repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q2UVF0
O75037

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
microtubule-based movement	IBA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cytoplasm	IBA
kinesin complex	IBA
microtubule	IBA
dendrite	IEA
growth cone	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

kinesin complex

cellular anatomical entity [inference]

cytoplasm

site of polarized growth [inference]

growth cone

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying **all 5** entries
GO Term	Evidence Code	PMID
microtubule motor activity	IBA
protein binding	IPI	32296183
ATP binding	IEA
microtubule binding	IBA
ATP hydrolysis activity	IBA

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

microtubule binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Kinesin

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
cytoskeletal motor activity
microtubule binding
microtubule-based movement
nucleotide binding

Displaying **all 5** entries
InterPro
Kinesin motor domain superfamily
Kinesin motor domain, conserved site
Kinesin motor domain
Kinesin-like protein
P-loop containing nucleoside triphosphate hydrolase

Ortholog

Displaying entries **31 - 40** of 78 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mustela putorius furo	101687803		MUSPF11839
Melopsittacus undulatus	101867849		MELUD18087
Chinchilla lanigera	102008285		CHILA01609
Macaca fascicularis	102129857		MACFA20091
Capra hircus	102174234		CAPHI32081
Haplochromis burtoni	102296350		HAPBU05306
Latimeria chalumnae	102346165		LATCH18770
Neolamprologus brichardi	102777424		NEOBR04447
Astyanax mexicanus	103045846		ASTMX05535
Chlorocebus sabaeus	103230341		CHLSB12089

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025