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G3BP stress granule assembly factor 2

Summary

Gene Symbol

G3bp2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

23881

PubChem

23881

Alliance of Genome Resources

MGI:2442040

Annotation

Keyword

Alternative splicing
Cytoplasm
Innate immunity
Isopeptide bond
Methylation
Phosphoprotein
RNA-binding
Reference proteome
Ubl conjugation
mRNA transport

Proteins

Displaying **all 5** entries
UniProt	Protein Name
Q542W3
Q3U6B1
P97379	GAP SH3 domain-binding protein 2
Q3TEL4
Q3U541

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
mRNA transport	IEA
stress granule assembly	IBA ISO ISS
positive regulation of stress granule assembly	IEA ISO
innate immune response	IEA
small GTPase mediated signal transduction	ISO	9575347

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

stress granule assembly

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

stress granule assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

localization [inference]

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

mRNA transport

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

mRNA transport

establishment of RNA localization [inference]

RNA transport [inference]

mRNA transport

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

regulation of organelle assembly [inference]

regulation of stress granule assembly [inference]

positive regulation of stress granule assembly

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

regulation of organelle assembly [inference]

regulation of stress granule assembly [inference]

positive regulation of stress granule assembly

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytoplasmic stress granule	IBA IEA ISO
ribonucleoprotein complex
cytosol	IBA IEA ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

ribonucleoprotein complex

cellular anatomical entity [inference]

cytosol

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

cytoplasmic stress granule

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

cytoplasmic stress granule

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

cytoplasmic stress granule

Displaying **all 3** entries
GO Term	Evidence Code	PMID
mRNA binding	IBA
RNA binding	IEA
molecular condensate scaffold activity	IBA ISO ISS

GO Hierarchy

molecular function

binding [inference]

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

mRNA binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

molecular condensate scaffold activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Ras GTPase-activating protein-binding protein

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
V: Defense mechanisms

Displaying **all 4** entries
Gene Ontology
molecular condensate scaffold activity
positive regulation of stress granule assembly
protein homooligomerization
stress granule assembly

Displaying **all 8** entries
InterPro
G3BP2, RNA recognition motif
NTF2-like domain superfamily
Nuclear transport factor 2 domain
Nuclear transport factor 2, eukaryote
Nucleotide-binding alpha-beta plait domain superfamily
RNA recognition motif domain
RNA-binding domain superfamily
Ras GTPase-activating protein-binding protein

Ortholog

Displaying entries **1 - 10** of **125** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	9908		HGNC:30291	HUMAN75947
Drosophila melanogaster	47998		FB:FBgn0015778
Caenorhabditis elegans	177880		WB:WBGene00010677
Rattus norvegicus	305240	10116_1:00443b	RGD:1309571	RATNO08758
Xenopus tropicalis	394887		Xenbase:XB-GENE-480361
Danio rerio	406683		ZFIN:ZDB-GENE-040426-2698
Pan troglodytes	461244			PANTR33720
Canis lupus familiaris	478429			CANLF12979
Bos taurus	539249			BOVIN31685
Danio rerio	556409		ZFIN:ZDB-GENE-070112-1972	DANRE17430