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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
T cell lymphoma invasion and metastasis 2
Summary
- Gene Symbol
-
- Tiam2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell projection
- Coiled coil
- Cytoplasm
- Guanine-nucleotide releasing factor
- Myristate
- Phosphoprotein
- Reference proteome
- Repeat
- Proteins
| UniProt | Protein Name |
|---|---|
| Q6ZPF3 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of axonogenesis | ||
| activation of GTPase activity | ||
| small GTPase mediated signal transduction |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| perikaryon | ||
| filopodium | ||
| lamellipodium | ||
| growth cone |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| GTPase activator activity | ||
| protein binding | ||
| guanyl-nucleotide exchange factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- rho guanine nucleotide exchange factor TIAM2
- Functional Category
-
- K: Transcription
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| positive regulation of axonogenesis |
| small GTPase-mediated signal transduction |
| InterPro |
|---|
| PH-like domain superfamily |
| Tiam1/Tiam2/Protein still life |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070354 | cataract 48 | |
| DOID:0070444 | neurodevelopmental disorder with language delay and seizures |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 26230 | HGNC:11806 | HUMAN87137 | ||
| 43892 | FB:FBgn0085447 | |||
| 259373 | WB:WBGene00015704 | |||
| 472168 | PANTR39361 | |||
| 701688 | MACMU35375 | |||
| 100032275 | MONDO11798 | |||
| 100061852 | HORSE29962 | |||
| 100079759 | ORNAN15368 | |||
| 100139161 | BOVIN36021 | |||
| 100155014 | PIGXX13187 |
