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toll-like receptor 2
Summary
- Gene Symbol
-
- Tlr2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cytoplasmic vesicle
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Inflammatory response
- Innate immunity
- Isopeptide bond
- Leucine-rich repeat
- NAD
- Proteomics identification
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| immune system process | ||
| cellular response to lipoteichoic acid | ||
| positive regulation of intracellular signal transduction | ||
| defense response | ||
| regulation of dendritic cell cytokine production |
GO Hierarchy
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of cellular response to macrophage colony-stimulating factor stimulus
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of cellular response to macrophage colony-stimulating factor stimulus
biological process
immune system process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
response to external stimulus [inference]
response to biotic stimulus [inference]
response to chemical [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of immune effector process [inference]
regulation of immune response [inference]
immune response-regulating signaling pathway [inference]
regulation of innate immune response [inference]
positive regulation of immune response [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production
positive regulation of gene expression
positive regulation of cytokine production
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production
positive regulation of gene expression
positive regulation of cytokine production
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production
positive regulation of gene expression
positive regulation of cytokine production
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
positive regulation of response to stimulus [inference]
positive regulation of response to biotic stimulus [inference]
positive regulation of defense response [inference]
positive regulation of response to external stimulus [inference]
positive regulation of immune response [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of response to biotic stimulus [inference]
regulation of signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
positive regulation of response to biotic stimulus [inference]
positive regulation of defense response [inference]
positive regulation of response to external stimulus [inference]
positive regulation of immune response [inference]
regulation of immune response [inference]
immune response-regulating signaling pathway [inference]
regulation of innate immune response [inference]
positive regulation of immune response [inference]
regulation of response to cytokine stimulus [inference]
regulation of response to stress [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production
positive regulation of gene expression
positive regulation of cytokine production
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production
| GO Term | Evidence Code | PMID |
|---|---|---|
| receptor complex | ||
| cell body | ||
| cytoplasm | ||
| external side of plasma membrane | ||
| Toll-like receptor 1-Toll-like receptor 2 protein complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| transmembrane signaling receptor activity | ||
| diacyl lipopeptide binding | ||
| lipopeptide binding | ||
| NAD+ nucleotidase, cyclic ADP-ribose generating |
|
|
| amyloid-beta binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050127 | sinusitis | |
| DOID:0050855 | renal fibrosis | |
| DOID:0060189 | ileitis | |
| DOID:0060224 | atrial fibrillation | |
| DOID:0060322 | mastoiditis | |
| DOID:0080176 | meningococcal meningitis | |
| DOID:0080784 | urinary tract infection | |
| DOID:0080998 | acute necrotizing pancreatitis | |
| DOID:10140 | dry eye syndrome | |
| DOID:10223 | dermatomyositis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 34761 | FB:FBgn0026760 | ||
| 40245 | FB:FBgn0036978 | ||
| 43222 | FB:FBgn0262473 | ||
| 103185499 | CALMI32336 | ||
| 102367073 | LATCH07288 | ||
| 403125 | ZFIN:ZDB-GENE-040219-6 | ||
| 102076916 | ORENI62318 | ||
| 102077009 | ORENI62319 | ||
| 109202487 | ORENI62320 | ||
| 113024418 | ASTCA34996 |
