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aldehyde dehydrogenase 1 family, member A1

Summary

Gene Symbol

Aldh1a1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

24188

PubChem

24188

Alliance of Genome Resources

RGD:2087

Annotation

Keyword

Acetylation
Cell projection
Cytoplasm
Direct protein sequencing
Lipid metabolism
NAD
Oxidoreductase
Phosphoprotein
Proteomics identification
Reference proteome

Proteins

Displaying **all 3** entries
UniProt	Protein Name
P51647	3-deoxyglucosone dehydrogenase ALDH-E1 ALHDII Aldehyde dehydrogenase family 1 member A1 Aldehyde dehydrogenase, cytosolic Retinal dehydrogenase 1
A6I0L3
A0A8I6AP49

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 15** of 40 in total

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GO Term	Evidence Code	PMID
response to oxidative stress	IMP	15623782
midgut development	IEP	15964596
response to xenobiotic stimulus	ISO
response to xenobiotic stimulus	IEP	10323328
response to xenobiotic stimulus	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

catabolic process [inference]

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

fructosamine catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

hormone metabolic process [inference]

retinol metabolic process

retinoic acid metabolic process

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process

9-cis-retinoic acid biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid metabolic process [inference]

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid biosynthetic process

retinoic acid metabolic process

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process

9-cis-retinoic acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

retinol metabolic process

retinoic acid metabolic process

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process

9-cis-retinoic acid biosynthetic process

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process [inference]

fructose catabolic process

hexose catabolic process [inference]

fructose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

retinol metabolic process

retinoic acid metabolic process

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process

9-cis-retinoic acid biosynthetic process

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process [inference]

fructose catabolic process

hexose catabolic process [inference]

fructose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

retinol metabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid metabolic process [inference]

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid biosynthetic process

retinoic acid metabolic process

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process

9-cis-retinoic acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process [inference]

fructose catabolic process

hexose catabolic process [inference]

fructose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid metabolic process [inference]

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid biosynthetic process

retinoic acid metabolic process

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process

9-cis-retinoic acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

retinol metabolic process

retinoic acid metabolic process

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process

9-cis-retinoic acid biosynthetic process

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

olefinic compound metabolic process [inference]

retinol metabolic process

carbohydrate derivative metabolic process [inference]

amino sugar metabolic process [inference]

fructosamine metabolic process [inference]

fructosamine catabolic process

amino sugar catabolic process [inference]

fructosamine catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

fructosamine catabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

fructosamine catabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

retinol metabolic process

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid metabolic process [inference]

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid biosynthetic process

retinoic acid metabolic process

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process

9-cis-retinoic acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

gamma-aminobutyric acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

retinol metabolic process

retinoic acid metabolic process

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process

9-cis-retinoic acid biosynthetic process

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

cellular detoxification [inference]

cellular detoxification of aldehyde

reproductive process [inference]

multicellular organismal reproductive process [inference]

ovulation cycle [inference]

estrous cycle

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

maintenance of lens transparency

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

embryonic organ morphogenesis [inference]

embryonic eye morphogenesis

sensory organ morphogenesis [inference]

eye morphogenesis [inference]

embryonic eye morphogenesis

embryonic morphogenesis [inference]

morphogenesis of embryonic epithelium [inference]

optic cup morphogenesis involved in camera-type eye development

embryonic organ morphogenesis [inference]

embryonic eye morphogenesis

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of embryonic epithelium [inference]

optic cup morphogenesis involved in camera-type eye development

anatomical structure development [inference]

tube development [inference]

digestive tract development [inference]

midgut development

animal organ development [inference]

kidney development

gland development [inference]

liver development

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

maintenance of lens transparency

rhythmic process [inference]

ovulation cycle [inference]

estrous cycle

response to stimulus [inference]

response to stress [inference]

response to oxidative stress

response to chemical [inference]

response to xenobiotic stimulus

response to organic substance [inference]

response to organic cyclic compound

response to estradiol

response to lipid [inference]

response to alcohol [inference]

response to ethanol

response to oxygen-containing compound [inference]

response to alcohol [inference]

response to ethanol

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of cold-induced thermogenesis

regulation of cold-induced thermogenesis [inference]

negative regulation of cold-induced thermogenesis

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of cold-induced thermogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of cold-induced thermogenesis

regulation of cellular process [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of cold-induced thermogenesis

regulation of cold-induced thermogenesis [inference]

negative regulation of cold-induced thermogenesis

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

retinol metabolic process

retinoic acid metabolic process

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process

9-cis-retinoic acid biosynthetic process

detoxification [inference]

cellular detoxification [inference]

cellular detoxification of aldehyde

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
cytosol	ISS
cytosol	ISO
axon	ISS
axon	ISO
axon	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
retinal dehydrogenase activity	IDA	17167544 7832787
3-chloroallyl aldehyde dehydrogenase activity	ISO
3-chloroallyl aldehyde dehydrogenase activity	TAS	8543180
3-chloroallyl aldehyde dehydrogenase activity	IEA
aldehyde dehydrogenase (NAD+) activity	ISO