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aldehyde dehydrogenase 1 family, member A1

Summary

Gene Symbol

Aldh1a1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

24188

KEGG Gene ID

PubChem

24188

Alliance of Genome Resources

RGD:2087

Annotation

Keyword

Acetylation
Cell projection
Cytoplasm
Direct protein sequencing
Lipid metabolism
NAD
Oxidoreductase
Phosphoprotein
Proteomics identification
Reference proteome

Proteins

Displaying **all 3** entries
UniProt	Protein Name
P51647	3-deoxyglucosone dehydrogenase ALDH-E1 ALHDII Aldehyde dehydrogenase family 1 member A1 Aldehyde dehydrogenase, cytosolic Retinal dehydrogenase 1
A6I0L3
A0A8I6AP49

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 37 in total

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GO Term	Evidence Code	PMID
retinoid metabolic process	IDA
kidney development	IEP
liver development	IEP
optic cup morphogenesis involved in camera-type eye development	ISO
retinoic acid biosynthetic process	IMP

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

aldehyde metabolic process

catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

fructosamine catabolic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

amino acid biosynthetic process [inference]

GABA biosynthetic process

small molecule biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

non-proteinogenic amino acid biosynthetic process [inference]

GABA biosynthetic process

hormone metabolic process [inference]

retinol metabolic process

retinoic acid metabolic process

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process

9-cis-retinoic acid biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process [inference]

fructose catabolic process

hexose catabolic process [inference]

fructose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

GABA biosynthetic process

non-proteinogenic amino acid metabolic process [inference]

non-proteinogenic amino acid biosynthetic process [inference]

GABA biosynthetic process

lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

retinol metabolic process

retinoic acid metabolic process

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process

9-cis-retinoic acid biosynthetic process

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process [inference]

fructose catabolic process

hexose catabolic process [inference]

fructose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

retinol metabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

retinoic acid metabolic process

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process

9-cis-retinoic acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

non-proteinogenic amino acid biosynthetic process [inference]

GABA biosynthetic process

non-proteinogenic amino acid metabolic process [inference]

non-proteinogenic amino acid biosynthetic process [inference]

GABA biosynthetic process

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

small molecule biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

non-proteinogenic amino acid biosynthetic process [inference]

GABA biosynthetic process

olefinic compound metabolic process [inference]

retinol metabolic process

carbohydrate derivative metabolic process [inference]

amino sugar metabolic process [inference]

fructosamine metabolic process [inference]

fructosamine catabolic process

amino sugar catabolic process [inference]

fructosamine catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

fructosamine catabolic process

cell death [inference]

programmed cell death [inference]

apoptotic process

cellular detoxification [inference]

cellular detoxification of aldehyde

reproductive process [inference]

multicellular organismal reproductive process [inference]

ovulation cycle [inference]

estrous cycle

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

maintenance of lens transparency

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

embryonic organ morphogenesis [inference]

embryonic eye morphogenesis

sensory organ morphogenesis [inference]

eye morphogenesis [inference]

embryonic eye morphogenesis

embryonic morphogenesis [inference]

morphogenesis of embryonic epithelium [inference]

optic cup morphogenesis involved in camera-type eye development

embryonic organ morphogenesis [inference]

embryonic eye morphogenesis

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of embryonic epithelium [inference]

optic cup morphogenesis involved in camera-type eye development

anatomical structure development [inference]

animal gross anatomical part developmental process [inference]

tube development [inference]

digestive tract development [inference]

midgut development

animal organ development [inference]

kidney development

gland development

liver development

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

maintenance of lens transparency

rhythmic process [inference]

ovulation cycle [inference]

estrous cycle

response to stimulus [inference]

response to stress [inference]

response to oxidative stress

response to chemical [inference]

response to xenobiotic stimulus

response to lipid [inference]

response to oxygen-containing compound [inference]

response to alcohol [inference]

response to ethanol

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

negative regulation of biological process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of cold-induced thermogenesis

regulation of cellular process [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of cold-induced thermogenesis

regulation of cold-induced thermogenesis [inference]

negative regulation of cold-induced thermogenesis

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

retinol metabolic process

retinoic acid metabolic process

retinoic acid biosynthetic process

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process

9-cis-retinoic acid biosynthetic process

detoxification [inference]

cellular detoxification [inference]

cellular detoxification of aldehyde

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
cytosol	ISS
cytosol	ISO
cytosol	IBA
cytosol	IEA
axon	ISS

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

Displaying entries **1 - 5** of 27 in total

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GO Term	Evidence Code	PMID
retinal dehydrogenase (NAD+) activity	IDA
retinal dehydrogenase (NAD+) activity	IEA
3-chloroallyl aldehyde dehydrogenase activity	ISO
3-chloroallyl aldehyde dehydrogenase activity	TAS
3-chloroallyl aldehyde dehydrogenase activity	IEA