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Submissions

isovaleryl-CoA dehydrogenase

Summary

Gene Symbol

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

24513

PubChem

24513

Alliance of Genome Resources

RGD:2936

Annotation

Keyword

Acetylation
Direct protein sequencing
FAD
Mitochondrion
Oxidoreductase
Reference proteome
Transit peptide

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6HPD3	Butyryl-CoA dehydrogenase
P12007	Butyryl-CoA dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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2

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GO Term	Evidence Code	PMID
leucine metabolic process	TAS	2777793
leucine catabolic process	ISO
leucine catabolic process	IDA	6401713
leucine catabolic process	IBA
leucine catabolic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process

leucine catabolic process

branched-chain amino acid catabolic process

leucine catabolic process

alpha-amino acid metabolic process [inference]

leucine metabolic process

leucine catabolic process

alpha-amino acid catabolic process [inference]

leucine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

alpha-amino acid catabolic process [inference]

leucine catabolic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

alpha-amino acid catabolic process [inference]

leucine catabolic process

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

alpha-amino acid catabolic process [inference]

leucine catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

organic acid catabolic process [inference]

carboxylic acid catabolic process

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

alpha-amino acid catabolic process [inference]

leucine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

alpha-amino acid catabolic process [inference]

leucine catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

alpha-amino acid catabolic process [inference]

leucine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process

leucine catabolic process

branched-chain amino acid catabolic process

leucine catabolic process

alpha-amino acid metabolic process [inference]

leucine metabolic process

leucine catabolic process

alpha-amino acid catabolic process [inference]

leucine catabolic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

carboxylic acid catabolic process

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

alpha-amino acid catabolic process [inference]

leucine catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

alpha-amino acid catabolic process [inference]

leucine catabolic process

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process

leucine catabolic process

branched-chain amino acid catabolic process

leucine catabolic process

alpha-amino acid metabolic process [inference]

leucine metabolic process

leucine catabolic process

alpha-amino acid catabolic process [inference]

leucine catabolic process

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

alpha-amino acid catabolic process [inference]

leucine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process

leucine catabolic process

branched-chain amino acid catabolic process

leucine catabolic process

alpha-amino acid metabolic process [inference]

leucine metabolic process

leucine catabolic process

alpha-amino acid catabolic process [inference]

leucine catabolic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

carboxylic acid catabolic process

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

alpha-amino acid catabolic process [inference]

leucine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

alpha-amino acid catabolic process [inference]

leucine catabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

alpha-amino acid catabolic process [inference]

leucine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process

leucine catabolic process

branched-chain amino acid catabolic process

leucine catabolic process

alpha-amino acid metabolic process [inference]

leucine metabolic process

leucine catabolic process

alpha-amino acid catabolic process [inference]

leucine catabolic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

carboxylic acid catabolic process

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

alpha-amino acid catabolic process [inference]

leucine catabolic process

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process

leucine catabolic process

branched-chain amino acid catabolic process

leucine catabolic process

alpha-amino acid metabolic process [inference]

leucine metabolic process

leucine catabolic process

alpha-amino acid catabolic process [inference]

leucine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

alpha-amino acid catabolic process [inference]

leucine catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

organic acid catabolic process [inference]

carboxylic acid catabolic process

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

alpha-amino acid catabolic process [inference]

leucine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

alpha-amino acid catabolic process [inference]

leucine catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

alpha-amino acid catabolic process [inference]

leucine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process

leucine catabolic process

branched-chain amino acid catabolic process

leucine catabolic process

alpha-amino acid metabolic process [inference]

leucine metabolic process

leucine catabolic process

alpha-amino acid catabolic process [inference]

leucine catabolic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

carboxylic acid catabolic process

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

alpha-amino acid catabolic process [inference]

leucine catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

leucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

alpha-amino acid catabolic process [inference]

leucine catabolic process

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
nucleoplasm	ISO
nucleoplasm	IEA
mitochondrion	ISO
mitochondrion	IBA
mitochondrion	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

nucleoplasm

membrane [inference]

organelle membrane [inference]

mitochondrial membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
acyl-CoA dehydrogenase activity	IEA
isovaleryl-CoA dehydrogenase activity	ISO
isovaleryl-CoA dehydrogenase activity	IDA	2777793 6401713
isovaleryl-CoA dehydrogenase activity	IBA
short-chain-acyl-CoA dehydrogenase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the CH-CH group of donors [inference]

oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor [inference]

acyl-CoA dehydrogenase activity

binding [inference]

protein binding [inference]

identical protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding

ion binding [inference]

anion binding [inference]

flavin adenine dinucleotide binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

acyl-CoA dehydrogenase

Functional Category

I: Lipid transport and metabolism
L: Replication, recombination and repair
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 3** entries
Gene Ontology
flavin adenine dinucleotide binding
oxidoreductase activity, acting on the CH-CH group of donors
oxidoreductase activity

Displaying **all 7** entries
InterPro
Acyl-CoA dehydrogenase-like, C-terminal
Acyl-CoA dehydrogenase/oxidase, C-terminal
Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily
Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily
Acyl-CoA dehydrogenase/oxidase, N-terminal
Acyl-CoA oxidase/dehydrogenase, middle domain superfamily
Acyl-CoA oxidase/dehydrogenase, middle domain

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
mitochondrial matrix	PMID:2777793

Ortholog

Displaying entries **1 - 10** of 76 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	3712		HUMAN22299
Xenopus tropicalis	24513	Xenbase:XB-GENE-1008677
Mus musculus	56357		MOUSE35980
Danio rerio	368775		DANRE12022
Pan troglodytes	453333		PANTR09979
Bos taurus	510440		BOVIN01020
Macaca mulatta	702867		MACMU42864
Monodelphis domestica	100031931		MONDO01937
Ornithorhynchus anatinus	100090657		ORNAN04492
Pongo abelii	100172441		PONAB09366

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Acknowledgements