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Fas apoptotic inhibitory molecule 2

Summary

Gene Symbol

Faim2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

246274

PubChem

246274

Alliance of Genome Resources

RGD:628744

Annotation

Keyword

Apoptosis
Cell membrane
Glycoprotein
Postsynaptic cell membrane
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
O88407	Fas apoptotic inhibitory molecule 2 Neural membrane protein 35
A6KCF9	Fas apoptotic inhibitory molecule 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entry **11 - 11** of 11 in total

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GO Term	Evidence Code	PMID
neuron apoptotic process	ISO

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

apoptotic signaling pathway

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

neuron apoptotic process

cellular developmental process [inference]

cell differentiation [inference]

cell differentiation in hindbrain [inference]

cerebellar Purkinje cell differentiation

neuron differentiation [inference]

central nervous system neuron differentiation [inference]

cerebellar Purkinje cell differentiation

developmental process [inference]

anatomical structure development [inference]

cellular developmental process [inference]

cell differentiation [inference]

cell differentiation in hindbrain [inference]

cerebellar Purkinje cell differentiation

neuron differentiation [inference]

central nervous system neuron differentiation [inference]

cerebellar Purkinje cell differentiation

response to stimulus [inference]

response to stress [inference]

response to ischemia

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of extrinsic apoptotic signaling pathway [inference]

regulation of extrinsic apoptotic signaling pathway via death domain receptors [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of extrinsic apoptotic signaling pathway [inference]

regulation of extrinsic apoptotic signaling pathway via death domain receptors [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of cellular process [inference]

signal transduction [inference]

apoptotic signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of extrinsic apoptotic signaling pathway [inference]

regulation of extrinsic apoptotic signaling pathway via death domain receptors [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of neuron apoptotic process

negative regulation of neuron apoptotic process

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of extrinsic apoptotic signaling pathway [inference]

regulation of extrinsic apoptotic signaling pathway via death domain receptors [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of apoptotic signaling pathway

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
membrane	IBA ISO
postsynaptic membrane	IEA
Golgi apparatus	IBA ISO
plasma membrane	IEA
membrane raft	ISO ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

membrane microdomain [inference]

membrane raft

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying 1 entry
GO Term	Evidence Code	PMID
calcium channel activity	IBA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

salt transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

protein lifeguard 2

Functional Category

C: Energy production and conversion
K: Transcription
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
negative regulation of apoptotic signaling pathway

Displaying 1 entry
InterPro
Bax inhibitor 1-related

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:3083	chronic obstructive pulmonary disease	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **122** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	23017		HGNC:17067	HUMAN12546
Mus musculus	72393	10090_1:004668	MGI:1919643	MOUSE16372
Caenorhabditis elegans	179361		WB:WBGene00009580
Caenorhabditis elegans	179362		WB:WBGene00006470
Caenorhabditis elegans	189842		WB:WBGene00021537
Pan troglodytes	451885			PANTR05920
Bos taurus	509790			BOVIN29227
Danio rerio	541391		ZFIN:ZDB-GENE-050320-88
Macaca mulatta	711559			MACMU05136
Macaca mulatta	711631			MACMU05136

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Last updated: December 9, 2024