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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
surfactant protein A1
Summary
- Gene Symbol
-
- Sftpa1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Collagen
- Direct protein sequencing
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Hydroxylation
- Lectin
- Metal-binding
- Reference proteome
- Repeat
- Signal
- Surface film
- Proteins
| UniProt | Protein Name |
|---|---|
| P08427 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to lipopolysaccharide | ||
| response to hyperoxia | ||
| response to retinoic acid | ||
| response to interleukin-6 | ||
| opsonization |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| multivesicular body | ||
| collagen trimer | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| carbohydrate binding |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- pulmonary surfactant-associated protein A
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| C-type lectin fold |
| C-type lectin, conserved site |
| C-type lectin-like/link domain superfamily |
| C-type lectin-like |
| Collectin, C-type lectin-like domain |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050127 | sinusitis | |
| DOID:0050156 | idiopathic pulmonary fibrosis | |
| DOID:11394 | adult respiratory distress syndrome | |
| DOID:11396 | pulmonary edema | |
| DOID:11650 | bronchopulmonary dysplasia | |
| DOID:12120 | pulmonary alveolar proteinosis | |
| DOID:12716 | newborn respiratory distress syndrome | |
| DOID:1273 | respiratory syncytial virus infectious disease | |
| DOID:13406 | pulmonary sarcoidosis | |
| DOID:1485 | cystic fibrosis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 127238305 | 109678_0:004857 | |||
| 127691081 | 10129_0:002a17 | |||
| 128108058 | 564181_0:000ab4 | |||
| 129669546 | 48139_1:004d1e | |||
| 130875194 | 269649_0:001880 | |||
| 131920162 | 42410_0:003302 |
