GlyCosmos Portal

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GO Term	Evidence Code	PMID
epidermal growth factor receptor binding	ISS
epidermal growth factor receptor binding	ISO
epidermal growth factor receptor binding	TAS	11487584 2103501
epidermal growth factor receptor binding	IDA	3299049
epidermal growth factor receptor binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

receptor ligand activity

growth factor activity

growth factor receptor binding [inference]

epidermal growth factor receptor binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity [inference]

transmembrane receptor protein tyrosine kinase activator activity

kinase regulator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity [inference]

transmembrane receptor protein tyrosine kinase activator activity

protein kinase regulator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity [inference]

transmembrane receptor protein tyrosine kinase activator activity

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

transmembrane receptor protein tyrosine kinase activator activity

receptor ligand activity

growth factor activity

molecular function activator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity [inference]

transmembrane receptor protein tyrosine kinase activator activity

signaling receptor activator activity [inference]

transmembrane receptor protein tyrosine kinase activator activity

receptor ligand activity

growth factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

protransforming growth factor alpha

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
epidermal growth factor receptor signaling pathway
growth factor activity
positive regulation of cell population proliferation
positive regulation of mitotic nuclear division

Displaying 1 entry
InterPro
EGF-like domain

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
extracellular space	PMID:11487584

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1793	pancreatic cancer	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 39 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	7039	Xenbase:XB-GENE-852694	HUMAN63138
Mus musculus	21802	Xenbase:XB-GENE-852694	MOUSE50062
Xenopus tropicalis	24827	Xenbase:XB-GENE-852694
Sus scrofa	397484		PIGXX21854
Bos taurus	540388		BOVIN02177
Macaca mulatta	613031		MACMU08703
Pan troglodytes	737080		PANTR27843
Oryctolagus cuniculus	100009482		RABIT08557
Monodelphis domestica	100032790		MONDO05552
Pongo abelii	100172994		PONAB23409

GlyTouCan

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OrthoDB (Group)

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Acknowledgements