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tumor protein p53
Summary
- Gene Symbol
-
- Tp53
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Acetylation
- Activator
- Apoptosis
- Biological rhythms
- Cell cycle
- Cytoplasm
- Cytoskeleton
- DNA-binding
- Endoplasmic reticulum
- Isopeptide bond
- Metal-binding
- Methylation
- Mitochondrion
- Necrosis
- Nucleus
- Phosphoprotein
- Reference proteome
- Repressor
- Transcription regulation
- Tumor suppressor
- Ubl conjugation
- Zinc
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| ER overload response | ||
| cellular response to UV | ||
| heart development | ||
| double-strand break repair | ||
| response to ethanol |
GO Hierarchy
- viral process
- positive regulation of cell cycle
- negative regulation of cell growth
- positive regulation of cell cycle
- negative regulation of cell growth
- positive regulation of cell cycle
biological process
immune system process [inference]
metabolic process [inference]
nitrogen compound metabolic process [inference]
cellular metabolic process [inference]
primary metabolic process [inference]
organic substance metabolic process [inference]
cellular process [inference]
cell activation [inference]
signal transduction [inference]
intracellular signal transduction [inference]
apoptotic signaling pathway
cellular metabolic process [inference]
cellular response to stimulus [inference]
multicellular organismal process [inference]
developmental process [inference]
response to stimulus [inference]
response to stress [inference]
response to chemical [inference]
cellular response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of RNA biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of RNA biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of RNA biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of DNA metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of programmed cell death [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
negative regulation of cell population proliferation
negative regulation of cellular metabolic process [inference]
negative regulation of cell cycle [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction [inference]
intracellular signal transduction [inference]
apoptotic signaling pathway
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of RNA biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell population proliferation
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of programmed cell death [inference]
negative regulation of cellular process [inference]
negative regulation of cell population proliferation
negative regulation of cellular metabolic process [inference]
negative regulation of cell cycle [inference]
regulation of cellular component organization [inference]
regulation of cell cycle
regulation of mitotic cell cycle
regulation of cell cycle process [inference]
negative regulation of cell cycle process [inference]
regulation of cell cycle phase transition [inference]
negative regulation of cell cycle [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| ATP-dependent DNA/DNA annealing activity | ||
| enzyme binding | ||
| protein self-association |
|
|
| MDM2/MDM4 family protein binding | ||
| protein phosphatase 2A binding |
GO Hierarchy
molecular function
binding [inference]
protein binding
organic cyclic compound binding [inference]
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2513 | basal cell carcinoma | |
| DOID:2531 | hematologic cancer | |
| DOID:2626 | choroid plexus papilloma | |
| DOID:2671 | transitional cell carcinoma | |
| DOID:2729 | dyskeratosis congenita | |
| DOID:2870 | endometrial adenocarcinoma | |
| DOID:2871 | endometrial carcinoma | |
| DOID:2998 | testicular cancer | |
| DOID:3012 | Li-Fraumeni syndrome | |
| DOID:3068 | glioblastoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 2768677 | FB:FBgn0039044 | ||
| 102366539 | LATCH10910 | ||
| 102690789 | LEPOC07666 | ||
| 30590 | ZFIN:ZDB-GENE-990415-270 | DANRE35793 | |
| 100304476 | ICTPU23515 | ||
| 113570174 | ELEEL07547 | ||
| 106602901 | SALSA120216 | ||
| 115154926 | SALTR105039 | ||
| 431679 | Xenbase:XB-GENE-484286 | ||
| 101942845 | CHRPI27412 |
