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MIRAGE
Cd4 molecule
Summary
- Gene Symbol
-
- Cd4
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Palmitate
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of protein phosphorylation | ||
| adaptive immune response | ||
| cell adhesion | ||
| cell surface receptor signaling pathway | ||
| positive regulation of calcium ion transport into cytosol |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of transmembrane transport [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum lumen | ||
| endoplasmic reticulum membrane | ||
| plasma membrane | ||
| external side of plasma membrane | ||
| external side of plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| signaling receptor binding | ||
| zinc ion binding | ||
| zinc ion binding | ||
| lipid binding | ||
| coreceptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- CD4
- Functional Category
-
- G: Carbohydrate transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| MHC class II protein binding |
| T cell activation |
| interleukin-15-mediated signaling pathway |
| positive regulation of ERK1 and ERK2 cascade |
| protein tyrosine kinase binding |
| InterPro |
|---|
| Immunoglobulin-like domain superfamily |
| Immunoglobulin-like domain |
| Immunoglobulin-like fold |
| T cell CD4 receptor C-terminal region |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10303 | sialadenitis | |
| DOID:813 | septic arthritis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 920 | ZFIN:ZDB-GENE-100922-280 | ||
| 12504 | ZFIN:ZDB-GENE-100922-280 | ||
| 24932 | ZFIN:ZDB-GENE-100922-280 |
