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hydroxysteroid 11-beta dehydrogenase 1

Summary

Gene Symbol

Hsd11b1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25116

PubChem

25116

Alliance of Genome Resources

RGD:2834

Annotation

Keyword

Alternative promoter usage
Direct protein sequencing
Endoplasmic reticulum
Glycoprotein
NADP
Oxidoreductase
Reference proteome
Signal
Signal-anchor
Steroid metabolism
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6JH26	7-oxosteroid reductase Corticosteroid 11-beta-dehydrogenase isozyme 1
P16232	7-oxosteroid reductase Corticosteroid 11-beta-dehydrogenase isozyme 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
glucocorticoid biosynthetic process	IDA	12460758
steroid catabolic process	IBA
glucocorticoid catabolic process	IDA	12460758
mineralocorticoid metabolic process	IDA	2808402
lung development	ISO

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

organic substance catabolic process [inference]

lipid catabolic process [inference]

steroid catabolic process

glucocorticoid catabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process

glucocorticoid catabolic process

biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

hormone metabolic process [inference]

mineralocorticoid metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

steroid catabolic process

glucocorticoid catabolic process

glucocorticoid metabolic process [inference]

mineralocorticoid metabolic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

lipid catabolic process [inference]

steroid catabolic process

glucocorticoid catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

steroid catabolic process

glucocorticoid catabolic process

glucocorticoid metabolic process [inference]

mineralocorticoid metabolic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

lipid catabolic process [inference]

steroid catabolic process

glucocorticoid catabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

steroid catabolic process

glucocorticoid catabolic process

glucocorticoid metabolic process [inference]

mineralocorticoid metabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process

glucocorticoid catabolic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

steroid catabolic process

glucocorticoid catabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process

glucocorticoid catabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

cellular process [inference]

mineralocorticoid metabolic process

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to estradiol stimulus

cellular response to oxygen-containing compound [inference]

cellular response to estradiol stimulus

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

lung development

response to stimulus [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels

response to chemical [inference]

response to organic substance [inference]

response to organic cyclic compound [inference]

response to estradiol [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to estradiol stimulus

response to lipid [inference]

response to estradiol [inference]

cellular response to estradiol stimulus

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to estradiol stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to estradiol stimulus

cellular response to oxygen-containing compound [inference]

cellular response to estradiol stimulus

response to oxygen-containing compound [inference]

response to estradiol [inference]

cellular response to estradiol stimulus

cellular response to oxygen-containing compound [inference]

cellular response to estradiol stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to estradiol stimulus

cellular response to oxygen-containing compound [inference]

cellular response to estradiol stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of catabolic process [inference]

regulation of carbohydrate catabolic process [inference]

regulation of pentose-phosphate shunt

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process [inference]

regulation of NADP metabolic process [inference]

regulation of pentose-phosphate shunt

regulation of generation of precursor metabolites and energy [inference]

regulation of pentose-phosphate shunt

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process [inference]

regulation of NADP metabolic process [inference]

regulation of pentose-phosphate shunt

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process [inference]

regulation of NADP metabolic process [inference]

regulation of pentose-phosphate shunt

regulation of amide metabolic process [inference]

regulation of pentose-phosphate shunt

regulation of small molecule metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process [inference]

regulation of NADP metabolic process [inference]

regulation of pentose-phosphate shunt

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of carbohydrate catabolic process [inference]

regulation of pentose-phosphate shunt

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process [inference]

regulation of NADP metabolic process [inference]

regulation of pentose-phosphate shunt

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process [inference]

regulation of NADP metabolic process [inference]

regulation of pentose-phosphate shunt

regulation of generation of precursor metabolites and energy [inference]

regulation of pentose-phosphate shunt

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process [inference]

regulation of NADP metabolic process [inference]

regulation of pentose-phosphate shunt

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

mineralocorticoid metabolic process

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	ISO
endoplasmic reticulum membrane	IBA
endoplasmic reticulum membrane	IEA
nuclear membrane	IDA	11250946
intracellular membrane-bounded organelle	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

apical part of cell

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
steroid binding	IBA
steroid binding	IPI	15761036
oxidoreductase activity	IEA
protein homodimerization activity	ISO
7-beta-hydroxysteroid dehydrogenase (NADP+) activity	IEA