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MIRAGE
11-beta-hydroxysteroid dehydrogenase 1

Summary
UniProt ID
P16232
Gene Symbol
  • Hsd11
  • Hsd11b1
Gene ID
25116
Organism
Rattus norvegicus (Norway rat)
PubChem
P16232
Re-Glyco
P16232
Annotation
Keyword
  • Alternative promoter usage
  • Direct protein sequencing
  • Endoplasmic reticulum
  • Glycoprotein
  • NADP
  • Oxidoreductase
  • Reference proteome
  • Signal-anchor
  • Steroid metabolism
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 4 entries
GO Term
nuclear membrane
intracellular membrane-bounded organelle
endoplasmic reticulum membrane
apical part of cell
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MKKYLLPVLVLCLGYYYSTNEEFRPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAGTMEDMAFAERFVVEAGKLLGGLDMLILNHITQTTMSLFHDDIHSVRRSMEVNFLSYVVLSTAALPMLKQSNGSIAIISSMAGKMTQPLIASYSASKFALDGFFSTIRKEHLMTKVNVSITLCVLGFIDTETALKETSGIILSQAAPKEECALEIIKGTVLRKDEVYYDKSSWTPLLLGNPGRRIMEFLSLRSYNRDLFVSN
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
158 N-linked (GlcNAc...) asparagine
203 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Glucocorticoid biosynthesis Rattus norvegicus
Prednisone ADME Rattus norvegicus
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:9970 obesity
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: March 31, 2025