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branched chain keto acid dehydrogenase E1 subunit alpha
Summary
- Gene Symbol
-
- Bckdha
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Acetylation
- Magnesium
- Metal-binding
- Mitochondrion
- Oxidoreductase
- Phosphoprotein
- Potassium
- Reference proteome
- Thiamine pyrophosphate
- Transit peptide
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| branched-chain amino acid catabolic process | ||
| response to nutrient | ||
| response to glucocorticoid | ||
| response to cAMP |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| oxoglutarate dehydrogenase complex | ||
| mitochondrion | ||
| mitochondrial matrix |
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
- Functional Category
-
- C: Energy production and conversion
- J: Translation, ribosomal structure and biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| branched-chain amino acid catabolic process |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor |
| oxidoreductase activity |
| InterPro |
|---|
| Dehydrogenase, E1 component |
| Thiamin diphosphate-binding fold |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9269 | maple syrup urine disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 101166649 | ORYLA03111 | |||
| 101574924 | 10160_0:004f91 | OCTDE26855 | ||
| 101606826 | 51337_0:004265 | JACJA22383 | ||
| 101692241 | MUSPF03224 | |||
| 101705928 | 10181_0:004a0b | HETGA16436 | ||
| 101835122 | 10036_0:00436c | |||
| 101937607 | CHRPI23838 | |||
| 101971149 | 43179_0:004e9c | ICTTR03123 | ||
| 101988841 | 79684_0:003333 | |||
| 102017818 | 34839_0:004a43 | CHILA23655 |
