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cytochrome c oxidase subunit 5A

Summary

Gene Symbol

Cox5a

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

252934

PubChem

252934

Alliance of Genome Resources

RGD:620607

Annotation

Keyword

Acetylation
Direct protein sequencing
Heme
Mitochondrion inner membrane
Phosphoprotein
Reference proteome
Transit peptide
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P11240	Cytochrome c oxidase polypeptide Va
A6J4V5	Cytochrome c oxidase polypeptide Va

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
mitochondrial electron transport, cytochrome c to oxygen	IBA
mitochondrial electron transport, cytochrome c to oxygen	IEA
proton transmembrane transport	IEA

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

cellular respiration [inference]

aerobic respiration [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, cytochrome c to oxygen

electron transport chain [inference]

respiratory electron transport chain [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, cytochrome c to oxygen

cellular process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

cellular respiration [inference]

aerobic respiration [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, cytochrome c to oxygen

electron transport chain [inference]

respiratory electron transport chain [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, cytochrome c to oxygen

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
mitochondrion	ISO
mitochondrial inner membrane	ISO
mitochondrial inner membrane	IEA
mitochondrial membrane	ISO
respiratory chain complex IV	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

respiratory chain complex [inference]

respiratory chain complex IV

catalytic complex [inference]

cytochrome complex [inference]

respiratory chain complex IV

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytochrome-c oxidase activity	TAS	2544858
cytochrome-c oxidase activity	IDA	7601105
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

electron transfer activity [inference]

cytochrome-c oxidase activity

oxidoreductase activity, acting on a heme group of donors [inference]

cytochrome-c oxidase activity

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

cytochrome-c oxidase activity

active monoatomic ion transmembrane transporter activity [inference]

cytochrome-c oxidase activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

cytochrome-c oxidase activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

oxidoreduction-driven active transmembrane transporter activity [inference]

cytochrome-c oxidase activity

active monoatomic ion transmembrane transporter activity [inference]

cytochrome-c oxidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cytochrome C oxidase

Functional Category

I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 3** entries
Gene Ontology
metal ion binding
mitochondrial electron transport, cytochrome c to oxygen
oxidative phosphorylation

Displaying **all 2** entries
InterPro
Cytochrome c oxidase, subunit Va/VI superfamily
Cytochrome c oxidase, subunit Va/VI

Ortholog

Displaying entries **11 - 20** of 30 in total

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Species	Gene ID	Orthologous MAtrix
Anolis carolinensis	100553736	ANOCA13284
Nomascus leucogenys	100588957	NOMLE32472
Cavia porcellus	100724348	CAVPO21760
Otolemur garnettii	100948614	OTOGA16504
Otolemur garnettii	100950124	OTOGA16504
Otolemur garnettii	100957909	OTOGA16504
Papio anubis	101006649	PAPAN36665
Gorilla gorilla gorilla	101134792	GORGO09533
Heterocephalus glaber	101714403	HETGA16606
Ictidomys tridecemlineatus	101971648	ICTTR13181