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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
aquaporin 2
Summary
- Gene Symbol
-
- Aqp2
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cell membrane
- Cytoplasmic vesicle
- Glycoprotein
- Golgi apparatus
- Phosphoprotein
- Reference proteome
- Repeat
- Transmembrane helix
- Transport
- Proteins
| UniProt | Protein Name |
|---|---|
| P34080 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| metanephric collecting duct development | ||
| cell volume homeostasis | ||
| response to calcium ion | ||
| cellular response to water deprivation | ||
| response to glucagon |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| recycling endosome | ||
| cytoplasmic vesicle | ||
| membrane | ||
| early endosome | ||
| Golgi apparatus |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| actin binding | ||
| glycerol transmembrane transporter activity | ||
| water transmembrane transporter activity | ||
| PDZ domain binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- aquaporin-2
- Functional Category
-
- G: Carbohydrate transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| water channel activity |
| InterPro |
|---|
| Aquaporin transporter |
| Aquaporin-like |
| Major intrinsic protein, conserved site |
| Major intrinsic protein |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081061 | nephrogenic diabetes insipidus type 2 | |
| DOID:10763 | hypertension | |
| DOID:12387 | nephrogenic diabetes insipidus | |
| DOID:1837 | diabetic ketoacidosis | |
| DOID:9409 | diabetes insipidus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 110547432 | 10047_0:000fa1 | |||
| 112920989 | VULVU13915 | |||
| 113195500 | 9999_0:00334b | |||
| 113447326 | PSETE20735 | |||
| 113491015 | ATHCN22090 | |||
| 113893109 | BOBOX40463 | |||
| 114029674 | VOMUR22395 | |||
| 114104023 | 93162_0:002ec1 | |||
| 114593013 | PODMU16605 | |||
| 114639557 | 491861_0:003b90 |
