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thyrotropin releasing hormone receptor

Summary

Gene Symbol

Trhr

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25570

PubChem

25570

Alliance of Genome Resources

RGD:3904

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q01717	Thyroliberin receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
positive regulation of protein-containing complex assembly	IDA	12023974
phospholipase C-activating G protein-coupled receptor signaling pathway	IBA
positive regulation of cytosolic calcium ion concentration	IDA	12023974
G protein-coupled receptor signaling pathway	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly

regulation of cellular component organization [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA
cell surface	IDA	12023974

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
identical protein binding	IPI	12023974
thyrotropin-releasing hormone receptor activity	IBA IDA IEA	12023974

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

identical protein binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

thyrotropin-releasing hormone receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

thyrotropin-releasing hormone receptor

Functional Category

H: Coenzyme transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
phospholipase C-activating G protein-coupled receptor signaling pathway
thyrotropin-releasing hormone receptor activity

Displaying **all 3** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Thyrotropin-releasing hormone receptor

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
cell surface	PMID:12023974

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0050328	congenital hypothyroidism	Alliance of Genome Resources
DOID:0111836	congenital nongoitrous hypothyroidism 7	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources

Ortholog

Displaying entries **31 - 40** of **133** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Saimiri boliviensis boliviensis	101037534		SAIBB30318
Takifugu rubripes	101073896		TAKRU45521
Felis catus	101088391		FELCA38128
Gorilla gorilla gorilla	101149528		GORGO40146
Octodon degus	101586694	10160_0:00349b	OCTDE18246
Jaculus jaculus	101614887	51337_0:000eb9	JACJA12987
Mustela putorius furo	101674583		MUSPF05300
Heterocephalus glaber	101723120	10181_0:001e76
Ficedula albicollis	101813340		FICAL04471
Mesocricetus auratus	101827570	10036_0:0038ae

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements