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thyrotropin releasing hormone receptor

Summary

Gene Symbol

Trhr

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25570

PubChem

25570

Alliance of Genome Resources

RGD:3904

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q01717	Thyroliberin receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
positive regulation of protein-containing complex assembly	IDA	12023974
phospholipase C-activating G protein-coupled receptor signaling pathway	IBA
positive regulation of cytosolic calcium ion concentration	IDA	12023974
G protein-coupled receptor signaling pathway	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly

regulation of cellular component organization [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA
cell surface	IDA	12023974

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
identical protein binding	IPI	12023974
thyrotropin-releasing hormone receptor activity	IBA IDA IEA	12023974

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

identical protein binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

thyrotropin-releasing hormone receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

thyrotropin-releasing hormone receptor

Functional Category

H: Coenzyme transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
phospholipase C-activating G protein-coupled receptor signaling pathway
thyrotropin-releasing hormone receptor activity

Displaying **all 3** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Thyrotropin-releasing hormone receptor

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
cell surface	PMID:12023974

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0050328	congenital hypothyroidism	Alliance of Genome Resources
DOID:0111836	congenital nongoitrous hypothyroidism 7	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources

Ortholog

Displaying entries **61 - 70** of **133** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Papio anubis	103887040		PAPAN39264
Rhinopithecus roxellana	104662149		RHIRO36079
Fukomys damarensis	104859062	885580_0:000811
Esox lucius	105031319		ESOLU58286
Pteropus vampyrus	105298299		PTEVA06244
Macaca nemestrina	105475977		MACNE11518
Mandrillus leucophaeus	105530715		MANLE32305
Cercocebus atys	105584508		CERAT15492
Aotus nancymaae	105710825		AOTNA12265
Propithecus coquereli	105811178		PROCO08819

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements