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leiomodin 1
Summary
- Gene Symbol
-
- LMOD1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Actin-binding
- Alternative splicing
- Cytoskeleton
- Disease variant
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repeat
- Proteins
| UniProt | Protein Name |
|---|---|
| P29536 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| pointed-end actin filament capping |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
regulation of actin filament-based process [inference]
regulation of cellular component biogenesis [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytosol | ||
| cytosol | ||
| cytoskeleton | ||
| striated muscle thin filament | ||
| actin filament |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin binding | ||
| tropomyosin binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- leiomodin-1
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| actin binding |
| actin filament organization |
| muscle contraction |
| myofibril assembly |
| pointed-end actin filament capping |
| tropomyosin binding |
| InterPro |
|---|
| Leucine-rich repeat domain superfamily |
| Tropomodulin |
| WH2 domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060610 | megacystis-microcolon-intestinal hypoperistalsis syndrome |
