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galactosylceramidase

Summary

Gene Symbol

GALC

Aliases

Krabbe disease

Organism

Homo sapiens (human)

External Links

NCBI Gene

2581

HGNC

4115

KEGG Gene ID

hsa:2581

PubChem

2581

Alliance of Genome Resources

HGNC:4115

Annotation

Keyword

Alternative splicing
Direct protein sequencing
Disease variant
Disulfide bond
Glycoprotein
Glycosidase
Leukodystrophy
Lipid degradation
Lysosome
Reference proteome
Signal
Sphingolipid metabolism

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A0A0MQV0	Galactosylceramidase
P54803	Galactocerebroside beta-galactosidase Galactosylceramidase Galactosylceramide beta-galactosidase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
myelination	IEA
glycosphingolipid catabolic process	TAS
galactosylceramide catabolic process	IBA IDA ISS	8399327

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

galactolipid metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

galactolipid metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

galactolipid metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

galactolipid metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

galactolipid metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

galactolipid metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular process [inference]

ensheathment of neurons [inference]

axon ensheathment [inference]

myelination

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

galactolipid metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
lysosomal lumen	TAS
lysosome	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying 1 entry
GO Term	Evidence Code	PMID
galactosylceramidase activity	IBA IDA ISS TAS	8281145 8399327

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

galactosylceramidase activity

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000054983

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K01202

Name

galactosylceramidase [EC:3.2.1.46]

References

8281145

Rhea

H₂O + a β-D-galactosyl-(1↔1ʼ)-N-acylsphing-4-enine

D-galactose + an N-acylsphing-4-enine

Enzyme

3.2.1.46

PMID

Disease

Disease Ontology

Displaying entries **51 - 60** of 82 in total

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DO ID	Disease Name	Source
DOID:2377	multiple sclerosis	DisGeNET
DOID:2752	glycogen storage disease II	DisGeNET DisGeNET
DOID:2786	cerebellar disease	DisGeNET
DOID:2848	obsolete melancholia	DisGeNET DisGeNET DisGeNET
DOID:3083	chronic obstructive pulmonary disease	DisGeNET
DOID:3211	lysosomal storage disease	DisGeNET
DOID:3213	demyelinating disease	DisGeNET
DOID:3225	tracheal disease	DisGeNET
DOID:3312	bipolar disorder	DisGeNET
DOID:3683	lung benign neoplasm	DisGeNET

The Human Phenotype Ontology

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HPO ID	HPO Term
HP:0002355	Difficulty walking
HP:0002359	Frequent falls
HP:0002361	Psychomotor deterioration
HP:0002371	Loss of speech
HP:0002373	Febrile seizure (within the age range of 3 months to 6 years)
HP:0002376	Developmental regression
HP:0002418	Abnormal midbrain morphology
HP:0002421	Poor head control
HP:0002445	Tetraplegia
HP:0002492	Abnormal corticospinal tract morphology

Displaying **all 4** entries
Disease ID	Disease Name
ORPHA:206443	late-infantile/juvenile Krabbe disease
ORPHA:206448	adult Krabbe disease
ORPHA:206436	infantile Krabbe disease
OMIM:245200	Krabbe disease

PubChem Disease

GHR Health Conditions

Krabbe disease

MedGen Diseases

Galactosylceramide beta-galactosidase deficiency

OMIM Phenotypes

KRABBE DISEASE; KRB

KEGG Diseases

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP002432
Gene Name: galactosylceramidase

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Meleagris gallopavo	100549468		MELGA11044
Serinus canaria	103826899		SERCA04262
Sarcophilus harrisii	100915302		SARHA17843
Callithrix jacchus	100412515		CALJA01879
Cercocebus atys	105596538		CERAT08819
Macaca fascicularis	101925411		MACFA39774
Macaca mulatta	693322		MACMU41553
Macaca nemestrina	105467587		MACNE10970
Papio anubis	100997466		PAPAN37914
Mandrillus leucophaeus	105535270		MANLE11337

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Last updated: August 19, 2024