GlyCosmos Portal

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GO Term	Evidence Code	PMID
nucleotide binding	IEA
purinergic nucleotide receptor activity	IEA
CTP binding	IDA	28332633
extracellularly ATP-gated monoatomic cation channel activity	IDA	12127972 14580944 25175421 25597706 28332633
extracellularly ATP-gated monoatomic cation channel activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

ligand-gated monoatomic ion channel activity

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

ligand-gated monoatomic cation channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

ligand-gated monoatomic ion channel activity

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

ligand-gated monoatomic cation channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

ligand-gated monoatomic cation channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

ATP-gated ion channel activity

extracellularly ATP-gated monoatomic cation channel activity

binding [inference]

protein binding [inference]

identical protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding

purine nucleotide binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

pyrimidine nucleotide binding [inference]

pyrimidine ribonucleotide binding [inference]

CTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

pyrimidine ribonucleotide binding [inference]

CTP binding

ion binding [inference]

anion binding [inference]

CTP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding

purine nucleotide binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

pyrimidine nucleotide binding [inference]

pyrimidine ribonucleotide binding [inference]

CTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

pyrimidine ribonucleotide binding [inference]

CTP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

pyrimidine ribonucleotide binding [inference]

CTP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

nucleotide receptor activity [inference]

purinergic nucleotide receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

P2x purinoceptor

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
ATP binding
calcium ion transmembrane transport
excitatory postsynaptic potential
extracellularly ATP-gated monoatomic cation channel activity
monoatomic ion channel activity
monoatomic ion transport
nucleotide binding
response to ATP

Displaying **all 2** entries
InterPro
P2X purinoreceptor extracellular domain superfamily
P2X purinoreceptor

Ortholog

Displaying entries **1 - 10** of 63 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5025	Xenbase:XB-GENE-967965	HUMAN15907
Mus musculus	18438	Xenbase:XB-GENE-967965	MOUSE43460
Rattus norvegicus	29659	Xenbase:XB-GENE-967965	RATNO05042
Xenopus tropicalis	259258	Xenbase:XB-GENE-967965
Bos taurus	338036		BOVIN09473
Xenopus tropicalis	398206	Xenbase:XB-GENE-967965
Canis lupus familiaris	448783		CANLF10290
Sus scrofa	497623		PIGXX06798
Macaca mulatta	702536		MACMU03941
Oryctolagus cuniculus	100008720		RABIT09132