SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
| UniProt | Protein Name |
|---|---|
| A0A2R8YCS7 |
|
| Q59H15 |
|
| Q9Y3Z3 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| double-strand break repair via homologous recombination | ||
| dGTP catabolic process | ||
| dGTP catabolic process | ||
| immune response | ||
| cellular response to DNA damage stimulus |
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| nucleus | ||
| nucleoplasm | ||
| nucleoplasm | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleic acid binding | ||
| single-stranded DNA binding | ||
| RNA binding | ||
| RNA nuclease activity | ||
| protein binding |
| Gene Ontology |
|---|
| 'de novo' IMP biosynthetic process |
| nucleotide binding |
| phosphoribosylaminoimidazolesuccinocarboxamide synthase activity |
| purine nucleotide biosynthetic process |
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050629 | Aicardi-Goutieres syndrome | |
| DOID:0060386 | Chilblain lupus | |
| DOID:1883 | hepatitis C | |
| DOID:2043 | hepatitis B | |
| DOID:9119 | acute myeloid leukemia |
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000054 | Micropenis |
| HP:0000252 | Microcephaly |
| HP:0000369 | Low-set ears |
| HP:0000444 | Convex nasal ridge |
| HP:0000496 | Abnormality of eye movement |
| HP:0000501 | Glaucoma |
| HP:0000508 | Ptosis |
| HP:0000625 | Eyelid coloboma |
| Disease ID | Disease Name |
|---|---|
| OMIM:614415 |
|
| OMIM:612952 |
|
| ORPHA:51 |
|
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 25939 | Xenbase:XB-GENE-976503 | ||
| 56045 | MOUSE33048 | ||
| 311580 | RATNO26819 | ||
| 458223 | PANTR24808 | ||
| 485862 | CANLF09514 | ||
| 524683 | BOVIN05214 | ||
| 553453 | DANRE24335 | ||
| 709060 | MACMU01455 | ||
| 100032613 | MONDO07533 | ||
| 100069764 | HORSE21662 |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
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Last updated: December 8, 2025