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kelch repeat and BTB domain containing 2

Summary

Gene Symbol

KBTBD2

Organism

Homo sapiens (human)

External Links

NCBI Gene

25948

PubChem

25948

Alliance of Genome Resources

HGNC:21751

Annotation

Keyword

3D-structure
Kelch repeat
Phosphoprotein
Reference proteome
Repeat
Ubl conjugation pathway

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8IY47	BTB and kelch domain-containing protein 1
A0A024RA38

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein K48-linked ubiquitination	IDA	27708159
protein ubiquitination
lipid metabolic process	IEA
regulation of cellular response to insulin stimulus	IDA	27708159
phosphatidylinositol 3-kinase/protein kinase B signal transduction	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K48-linked ubiquitination

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

lipid metabolic process

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K48-linked ubiquitination

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

lipid metabolic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K48-linked ubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K48-linked ubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K48-linked ubiquitination

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

phosphatidylinositol 3-kinase/protein kinase B signal transduction

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to oxygen-containing compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

biological regulation [inference]

regulation of biological process [inference]

regulation of response to stimulus [inference]

regulation of cellular response to insulin stimulus

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of cellular response to insulin stimulus

Displaying 1 entry
GO Term	Evidence Code	PMID
cytoplasm	IDA	27708159

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying 1 entry
GO Term	Evidence Code	PMID
ubiquitin ligase-substrate adaptor activity	IDA	27708159

GO Hierarchy

molecular function

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

enzyme-substrate adaptor activity [inference]

ubiquitin ligase-substrate adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **1 - 10** of 95 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Callorhinchus milii	103183402		CALMI27366
Latimeria chalumnae	102345948		LATCH10654
Danio rerio	563254	ZFIN:ZDB-GENE-060929-1262	DANRE04166
Astyanax mexicanus	103038199		ASTMX12654
Ictalurus punctatus	108273874		ICTPU05695
Electrophorus electricus	113588310		ELEEL41327
Salmo salar	106579707		SALSA59047
Salmo salar	106590311		SALSA102667
Salmo trutta	115149161		SALTR02132
Salmo trutta	115195673		SALTR95543