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kelch repeat and BTB domain containing 2

Summary

Gene Symbol

KBTBD2

Organism

Homo sapiens (human)

External Links

NCBI Gene

25948

PubChem

25948

Alliance of Genome Resources

HGNC:21751

Annotation

Keyword

3D-structure
Kelch repeat
Phosphoprotein
Reference proteome
Repeat
Ubl conjugation pathway

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8IY47	BTB and kelch domain-containing protein 1
A0A024RA38

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein K48-linked ubiquitination	IDA	27708159
protein ubiquitination
lipid metabolic process	IEA
regulation of cellular response to insulin stimulus	IDA	27708159
phosphatidylinositol 3-kinase/protein kinase B signal transduction	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K48-linked ubiquitination

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

lipid metabolic process

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K48-linked ubiquitination

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

lipid metabolic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K48-linked ubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K48-linked ubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K48-linked ubiquitination

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

phosphatidylinositol 3-kinase/protein kinase B signal transduction

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to oxygen-containing compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

biological regulation [inference]

regulation of biological process [inference]

regulation of response to stimulus [inference]

regulation of cellular response to insulin stimulus

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of cellular response to insulin stimulus

Displaying 1 entry
GO Term	Evidence Code	PMID
cytoplasm	IDA	27708159

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying 1 entry
GO Term	Evidence Code	PMID
ubiquitin ligase-substrate adaptor activity	IDA	27708159

GO Hierarchy

molecular function

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

enzyme-substrate adaptor activity [inference]

ubiquitin ligase-substrate adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **31 - 40** of 95 in total

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Species	Gene ID	Orthologous MAtrix
Gorilla gorilla gorilla	101154596	GORGO39435
Pan paniscus	100983383	PANPA36082
Pan troglodytes	463336	PANTR39985
Pongo abelii	100171836	PONAB32776
Canis lupus familiaris	119863910	CANLF03802
Vulpes vulpes	112935382	VULVU31689
Ursus americanus	123789088	URSAM29927
Ailuropoda melanoleuca	100472366	AILME10129
Mustela putorius furo	101693050	MUSPF09123
Panthera leo	122209605	PANLE21114