GlyCosmos Portal

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GO Term	Evidence Code	PMID
RNA 7-methylguanosine cap binding	IDA	17524464
RNA polymerase II complex binding	IDA	25336585
core promoter sequence-specific DNA binding	IMP	25336585
RNA binding	HDA	22658674 22681889
double-stranded RNA binding	IDA	19966796

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

nuclease activity [inference]

endonuclease activity [inference]

RNA endonuclease activity

RNA endonuclease activity, producing 5'-phosphomonoesters [inference]

endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters [inference]

RNA endonuclease activity, producing 5'-phosphomonoesters [inference]

RNA nuclease activity [inference]

RNA endonuclease activity

RNA endonuclease activity, producing 5'-phosphomonoesters [inference]

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA nuclease activity [inference]

RNA endonuclease activity

RNA endonuclease activity, producing 5'-phosphomonoesters [inference]

binding [inference]

protein binding

basal transcription machinery binding [inference]

basal RNA polymerase II transcription machinery binding [inference]

RNA polymerase II complex binding

enzyme binding [inference]

RNA polymerase binding [inference]

RNA polymerase core enzyme binding [inference]

RNA polymerase II complex binding

ion binding [inference]

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

transcription regulatory region nucleic acid binding [inference]

transcription cis-regulatory region binding [inference]

core promoter sequence-specific DNA binding

DNA binding [inference]

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

core promoter sequence-specific DNA binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

core promoter sequence-specific DNA binding

RNA binding

RNA cap binding [inference]

mRNA binding [inference]

mRNA 3'-UTR binding [inference]

mRNA 3'-UTR AU-rich region binding

mRNA cap binding

regulatory RNA binding [inference]

translation regulator activity, nucleic acid binding [inference]

translation factor activity, RNA binding [inference]

translation initiation factor activity

translation regulator activity [inference]

translation regulator activity, nucleic acid binding [inference]

translation factor activity, RNA binding [inference]

translation initiation factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

argonaute

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
RNA endonuclease activity
miRNA binding
regulatory ncRNA-mediated gene silencing

Displaying **all 10** entries
InterPro
Argonaute linker 2 domain
Argonaute, linker 1 domain
Argonaute-like, PIWI domain
PAZ domain superfamily
PAZ domain
Piwi domain
Protein argonaute, Mid domain
Protein argonaute, N-terminal
Ribonuclease H superfamily
Ribonuclease H-like superfamily

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0050741	alcohol dependence	Alliance of Genome Resources
DOID:1686	glaucoma	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements