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calcium sensing receptor

Summary

Gene Symbol

CASR

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 281038
PubChem: 281038

Annotation

Keyword

Calcium
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Metal-binding
Phosphoprotein
Reference proteome
Signal
Transmembrane helix
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P35384	Parathyroid cell calcium-sensing receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
positive regulation of cell population proliferation
regulation of calcium ion transport	IEA	30032202
intracellular calcium ion homeostasis	IEA	30032202
calcium ion transport

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

MAPK cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

cellular response to stimulus [inference]

cellular response to stress [inference]

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

multicellular organismal process [inference]

ossification

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

vasodilation

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

response to chemical [inference]

response to organic substance [inference]

response to calcium ion [inference]

detection of calcium ion

response to inorganic substance [inference]

response to metal ion [inference]

response to calcium ion [inference]

detection of calcium ion

response to oxygen-containing compound [inference]

response to calcium ion [inference]

detection of calcium ion

response to salt [inference]

response to calcium ion [inference]

detection of calcium ion

detection of stimulus [inference]

detection of chemical stimulus [inference]

detection of calcium ion

cellular response to stimulus [inference]

cellular response to stress [inference]

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport

organic substance transport [inference]

calcium ion transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

MAPK cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

vasodilation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA	30032202
axon terminus

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

neuron projection terminus [inference]

axon terminus

presynapse [inference]

axon terminus

Displaying **all 4** entries
GO Term	Evidence Code	PMID
amino acid binding
calcium ion binding	IEA	30032202
G protein-coupled receptor activity	IEA	22301074 30032202
protein homodimerization activity

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

amino acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

amino acid binding

cation binding [inference]

metal ion binding [inference]

calcium ion binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **71 - 80** of **101** in total

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Species	Gene ID	Orthologous MAtrix
Ictalurus punctatus	108260132	ICTPU23434
Pygocentrus nattereri	108430404	PYGNA13090
Rhinopithecus bieti	108541446	RHIBE18530
Cyprinus carpio carpio	109059878	CYPCA13635
Cyprinus carpio carpio	109106310	CYPCA17883
Crocodylus porosus	109316224	CROPO05210
Hippocampus comes	109517814	HIPCM09386
Phascolarctos cinereus	110208103	PHACI22388
Seriola dumerili	111234605	SERDU12806
Amphiprion ocellaris	111587194	AMPOC11861