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MIRAGE
Extracellular calcium-sensing receptor
Summary
- UniProt ID
- P35384
- Gene Symbol
-
- CASR
- GPRC2A
- PCAR1
- Gene ID
- 281038
- Organism
- Bos taurus (domestic cattle)
Annotation
- Keyword
-
- Calcium
- Cell membrane
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Metal-binding
- Phosphoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| axon terminus |
| glutamatergic synapse |
| GO Term |
|---|
| G protein-coupled receptor activity |
| calcium ion binding |
| amino acid binding |
| protein homodimerization activity |
Sequence
MALYSCCWILLAFSTWCTSAYGPDQRAQKKGDIILGGLFPIHFGVAVKDQDLKSRPESVECIRYNFRGFRWLQAMIFAIEEINSSPALLPNMTLGYRIFDTCNTVSKALEATLSFVAQNKIDSLNLDEFCNCSEHIPSTIAVVGATGSGISTAVANLLGLFYIPQVSYASSSRLLSNKNQFKSFLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERDICIDFSELISQYSDEEKIQQVVEVIQNSTAKVIVVFSSGPDLEPLIKEIVRRNITGRIWLASEAWASSSLIAMPEYFHVVGGTIGFGLKAGQIPGFREFLQKVHPRKSVHNGFAKEFWEETFNCHLQEGAKGPLPVDTFLRGHEEGGARLSNSPTAFRPLCTGEENISSVETPYMDYTHLRISYNVYLAVYSIAHALQDIYTCIPGRGLFTNGSCADIKKVEAWQVLKHLRHLNFTSNMGEQVTFDECGDLAGNYSIINWHLSPEDGSIVFKEVGYYNVYAKKGERLFINDEKILWSGFSREVPFSNCSRDCLAGTRKGIIEGEPTCCFECVECPDGEYSDETDASACDKCPDDFWSNENHTSCIAKEIEFLSWTEPFGIALTLFAVLGIFLTAFVLGVFIKFRNTPIVKATNRELSYLLLFSLLCCFSSSLFFIGEPQDWTCRLRQPAFGISFVLCISCILVKTNRVLLVFEAKIPTSFHRKWWGLNLQFLLVFLCTFMQIVICAIWLNTAPPSSYRNHELEDEIIFITCHEGSLMALGFLIGYTCLLAAICFFFAFKSRKLPENFNEAKFITFSMLIFFIVWISFIPAYASTYGKFVSAVEVIAILAASFGLLACIFFNKVYIILFKPSRNTIEEVRCSTAAHAFKVAARATLRRSNVSRQRSSSLGGSTGSTPSSSISSKSNSEDPFPQQQPKRQKQPQPLALSPHNAQQPQPRPPSTPQPQPQSQQPPRCKQKVIFGSGTVTFSLSFDEPQKTAVAHRNSTHQTSLEAQKNNDALTKHQALLPLQCGETDSELTSQETGLQGPVGEDHQLEMEDPEEMSPALVVSNSRSFVISGGGSTVTENMLRS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 91 | N-linked (GlcNAc...) asparagine |
|
||
| 131 | N-linked (GlcNAc...) asparagine |
|
||
| 262 | N-linked (GlcNAc...) asparagine |
|
||
| 288 | N-linked (GlcNAc...) asparagine |
|
||
| 401 | N-linked (GlcNAc...) asparagine |
|
||
| 447 | N-linked (GlcNAc...) asparagine |
|
||
| 469 | N-linked (GlcNAc...) asparagine |
|
||
| 489 | N-linked (GlcNAc...) asparagine |
|
||
| 542 | N-linked (GlcNAc...) asparagine |
|
||
| 595 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | Bos taurus |
| G alpha (i) signalling events | Bos taurus |
| G alpha (q) signalling events | Bos taurus |
