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MIRAGE
fatty acid synthase

Summary
Gene Symbol
  • FASN
Organism
Bos taurus (domestic cattle)
NCBI Gene
281152
KEGG Gene ID
bta:281152
PubChem
281152
Annotation
Keyword
  • Acetylation
  • Cytoplasm
  • Fatty acid biosynthesis
  • Hydrolase
  • Isopeptide bond
  • Lyase
  • Multifunctional enzyme
  • NAD
  • NADP
  • Oxidoreductase
  • Phosphopantetheine
  • Phosphoprotein
  • Pyridoxal phosphate
  • Reference proteome
  • S-nitrosylation
  • Transferase
  • Ubl conjugation
Proteins
Displaying 1 entry
UniProt Protein Name
Q71SP7
Annotation information from UniProt.
Gene Ontology (GO)
Displaying 1 entry
GO Term Evidence Code PMID
fatty acid biosynthetic process
GO Hierarchy
Displaying 1 entry
GO Term Evidence Code PMID
cytoplasm
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
polyketide synthase
Functional Category
  • I: Lipid transport and metabolism
  • J: Translation, ribosomal structure and biogenesis
  • Q: Secondary metabolites biosynthesis, transport and catabolism
Displaying all 4 entries
Gene Ontology
fatty acid synthase activity
oxidoreductase activity
phosphopantetheine binding
transferase activity
Displaying entries 1 - 10 of 20 in total
InterPro
ACP-like superfamily
Acyl transferase domain superfamily
Acyl transferase/acyl hydrolase/lysophospholipase
Acyl transferase
Beta-ketoacyl synthase, C-terminal
Beta-ketoacyl synthase, N-terminal
Beta-ketoacyl synthase, active site
GroES-like superfamily
Malonyl-CoA ACP transacylase, ACP-binding
NAD(P)-binding domain superfamily
KEGG BRITE Database
Orthology
K00665
Name
fatty acid synthase, animal type [EC:2.3.1.85]
References
Rhea

RHEA:14993

H+ + acetyl-CoA + malonyl-CoA + NADPH
CO2 + CoA + a long-chain fatty acid + NADP+
Enzyme
PMID
Ortholog
Displaying entries 1 - 10 of 64 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
2194 HUMAN37215
14104 MOUSE05379
50671 RATNO02489
397561 PIGXX01624
454986 PANTR15736
483378 CANLF18324
715708 MACMU14122
100025176 MONDO10804
100226957 TAEGU07255
100270775 FELCA31132
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025