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MIRAGE
beta-1,4-N-acetyl-galactosaminyltransferase 3

Summary
Gene Symbol
  • B4GALNT3
Aliases
  • B4GalNac-T3
  • FLJ16224
  • FLJ40362
Organism
Homo sapiens (human)
NCBI Gene
283358
GGDB ID
HGNC
24137
mRNA
map
  • 12p13.33
Protein
OMIM
KEGG Gene ID
hsa:283358
PubChem
283358
Alliance of Genome Resources
Annotation
Keyword
  • Glycosyltransferase
  • Golgi apparatus
  • Reference proteome
  • Signal-anchor
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
Q6L9W6
  • Beta-1,4-N-acetylgalactosaminyltransferase III
  • N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2
Q8N9V0
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1
Functional Category
  • O: Posttranslational modification, protein turnover, chaperones
  • Q: Secondary metabolites biosynthesis, transport and catabolism
  • T: Signal transduction mechanisms
Displaying all 3 entries
Gene Ontology
acetylgalactosaminyltransferase activity
hexosyltransferase activity
transferase activity
Displaying all 4 entries
InterPro
Chondroitin N-acetylgalactosaminyltransferase
Nucleotide-diphospho-sugar transferases
PA14 domain
PA14/GLEYA domain
Human Protein Atlas
ENSG00000139044

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas
GlycoGene Database (GGDB)
GGDB ID
gg106
Gene Symbol
  • B4GALNT3
Reactions
Displaying 1 entry
Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
UDP-GalNAc
G49108TO
R
G00057MO
R
Displaying all 5 entries
Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
UDP-GalNAc
G00033MO
[alpha]-pNP
G52144RR
[alpha]-pNP
UDP-GalNAc
G49108TO
R
G00057MO
R
UDP-GalNAc
G49108TO
[beta]-Bz
G00057MO
[beta]-Bz
UDP-GalNAc
G00035MO
[alpha]-pNP
G35179MW
[alpha]-pNP
UDP-GalNAc
G00041MO
[alpha]-pNP
G45849QU
[alpha]-pNP
Displaying entries 1 - 5 of 12 in total
Donor Acceptor Reducing terminal(Acceptor) Reference
UDP-GalNAc
G65889KE
[beta]-oNP
UDP-GalNAc
G57321FI
[alpha]-Bz
UDP-GalNAc
G16579HJ
[beta]-pNP
UDP-GalNAc
G09546QO
[alpha]-pNP
UDP-GalNAc
G93723GS
[beta]-pNP
Orthologous Gene
Displaying all 2 entries
Species Protein mRNA
Mus musculus NP_094510 NM_198884
Rattus norvegicus XP_575655 XM_575655
KEGG BRITE Database
Orthology
K09656
Name
beta-1,4-N-acetylgalactosaminyltransferase 3 [EC:2.4.1.244]
References
Reactions
Displaying all 2 entries
KEGG Reaction Enzyme Acceptor Product
R07610
R07611
Rhea

RHEA:20493

an N-acetyl-β-D-glucosaminyl derivative + UDP-N-acetyl-α-D-galactosamine
an N-acetyl-β-D-galactosaminyl-(1→4)-N-acetyl-β-D-glucosaminyl derivative + H+ + UDP
Enzyme
PMID
Ortholog
Displaying entries 31 - 40 of 71 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
102145263 MACFA02200
102172522 CAPHI25644
103116385 ERIEU10811
103266186 CARSF12199
103466673 POERE28865
103675765 URSMA24215
103739368 NANGA15270
104662541 RHIRO18611
105022210 ESOLU56846
105463809 MACNE45482
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025