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Glycan Structure Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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G00033MO
Summary
- GlyTouCan ID
-
G00033MO
- IUPAC Condensed
- Gal(b1-3)[GlcNAc(b1-6)]GalNAc(a1-
- Motifs
- O-Glycan core 2
- Subsumption Level
- Fully-defined saccharide
- Monoisotopic Mass
- 586.22
3D Structures
G00034MO
G24720OO
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Severe acute respiratory syndrome coronavirus 2 | |
| Drosophila melanogaster (fruit fly) |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B3GALNT2 | UDP-GalNAc |
G00033MO
|
Ser/Thr |
G01707KB
|
Ser/Thr | |
| GCNT1 | UDP-GlcNAc |
G00031MO
|
Ser/Thr (core 2) |
G00033MO
|
Ser/Thr (core 2) | |
| GCNT3 | UDP-GlcNAc |
G00031MO
|
Ser/Thr |
G00033MO
|
Ser/Thr | |
| GCNT4 | UDP-GlcNAc |
G00031MO
|
Ser/Thr |
G00033MO
|
Ser/Thr |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| ST3GAL1 | CMP-Neu5Ac |
G00033MO
|
O-glycan Synthesis |
G85608AG
|
O-glycan Synthesis | |
| FUT2 | GDP-Fuc |
G00033MO
|
O-glycan Synthesis |
G32426JY
|
O-glycan Synthesis | |
| B4GALT4 | UDP-Gal |
G00033MO
|
pNP |
G64973KT
|
pNP | |
| B4GALT1 | UDP-Gal |
G00033MO
|
O-glycan Synthesis |
G64973KT
|
O-glycan Synthesis | |
| B3GALNT2 | UDP-GalNAc |
G00033MO
|
(core2)-pNP |
G01707KB
|
(core2)-pNP |
KEGG BRITE Database
G27236KE
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| P01876 | Immunoglobulin heavy constant alpha 1 | ||
| P0DTC2 | Spike glycoprotein | ||
| P10761 | Zona pellucida sperm-binding protein 3 | ||
| P12259 | Coagulation factor V | ||
| P15941 | Mucin-1 | ||
| P20239 | Zona pellucida sperm-binding protein 2 | ||
| P21754 | Zona pellucida sperm-binding protein 3 | ||
| P35253 | Envelope glycoprotein | ||
| Q92954 | Proteoglycan 4 | ||
| Q9BYF1 | Angiotensin-converting enzyme 2 |
Sequence Descriptors
- GlycoCT
-
RES 1b:a-dgal-HEX-1:5 2s:n-acetyl 3b:b-dgal-HEX-1:5 4b:b-dglc-HEX-1:5 5s:n-acetyl LIN 1:1d(2+1)2n 2:1o(3+1)3d 3:1o(6+1)4d 4:4d(2+1)5n
- WURCS
- WURCS=2.0/3,3,2/[a2112h-1a_1-5_2*NCC/3=O][a2112h-1b_1-5][a2122h-1b_1-5_2*NCC/3=O]/1-2-3/a3-b1_a6-c1
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 35022400 | Mammalian brain glycoproteins exhibit diminished glycan complexity compared to other tissues | Williams SE | 2022 Jan 12 |
|
| 34191522 | The O-Glycome of Human Nigrostriatal Tissue and Its Alteration in Parkinson's Disease | Wilkinson H | 2021 Aug 6 |
|
| 33871970 | Structural and Functional Characterization of SARS-CoV-2 RBD Domains Produced in Mammalian Cells | Gstottner C | 2021 Apr 19 |
|
| 32841605 | Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor | Zhao P | 2020 Oct 07 |
|
| 32310329 | Comprehensive N- and O-glycosylation mapping of human coagulation factor V | Ma C | 2020 Aug |
|
| 31620994 | Structural Basis of Glycan Recognition in Globally Predominant Human P[8] Rotavirus | Sun X | 2019 Oct 09 |
|
| 31118252 | GII.13/21 noroviruses recognize glycans with a terminal beta-galactose via an unconventional glycan binding site | Cong X | 2019 May 22 |
|
| 29720519 | Glycan Binding Specificity and Mechanism of Human and Porcine P[6]/P[19] Rotavirus VP8*s | Sun X | 2018 Jul 15 |
|
| 25187573 | The O-glycomap of Lubricin, a Novel Mucin Responsible for Joint Lubrication, Identified by Site-specific Glycopeptide Analysis | Ali L | 2014 Dec |
|
| 21402433 | Synthesis of the carbohydrate moiety from the parasite Echinococcus multilocularis and their antigenicity against human sera | Koizumi A | 2011 May |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Recombinant MUC1 probe authentically reflects cell-specific O-glycosylation profiles of endogenous breast cancer mucin. High density and prevalent core 2-based glycosylation. |
|
J Biol Chem | 2002 Jul 19 | 12000758 |
| Specificities of N-acetylglucosamine-6-O-sulfotransferases in relation to L-selectin ligand synthesis and tumor-associated enzyme expression. |
|
J Biol Chem | 2002 Feb 8 | 11726653 |
| The relative activities of the C2GnT1 and ST3Gal-I glycosyltransferases determine O-glycan structure and expression of a tumor-associated epitope on MUC1. |
|
J Biol Chem | 2001 Apr 6 | 11118434 |
| MUC1 and cancer. |
|
Biochim Biophys Acta | 1999 Oct 8 | 10571020 |
| An alpha2,3 sialyltransferase (ST3Gal I) is elevated in primary breast carcinomas. |
|
Glycobiology | 1999 Dec | 10561455 |
