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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glutathione peroxidase 3
Summary
- Gene Symbol
-
- GPX3
- Aliases
-
- selenoprotein GPX3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Direct protein sequencing
- Peroxidase
- Reference proteome
- Secreted
- Selenocysteine
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P22352 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| hydrogen peroxide catabolic process | ||
| cellular oxidant detoxification | ||
| response to lipid hydroperoxide |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| extracellular space | ||
| extracellular exosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| selenium binding | ||
| identical protein binding | ||
| glutathione peroxidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Glutathione peroxidase
- Functional Category
-
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- V: Defense mechanisms
| Gene Ontology |
|---|
| cellular oxidant detoxification |
| oxidoreductase activity |
| response to oxidative stress |
| InterPro |
|---|
| Glutathione peroxidase conserved site |
| Glutathione peroxidase |
| Thioredoxin-like superfamily |
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4914 | esophagus adenocarcinoma | |
| DOID:4948 | gallbladder carcinoma | |
| DOID:5041 | esophageal cancer | |
| DOID:6713 | cerebrovascular disease | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:7941 | Barrett's adenocarcinoma | |
| DOID:850 | lung disease | |
| DOID:9206 | Barrett's esophagus | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9408 | acute myocardial infarction |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP001191
- Gene Name
- glutathione peroxidase 3 (plasma)
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 103749068 | NANGA19954 | |||
| 104670427 | RHIRO28119 | |||
| 105299460 | PTEVA14121 | |||
| 105466859 | MACNE08005 | |||
| 105543416 | MANLE16355 | |||
| 105589898 | CERAT28192 | |||
| 105714085 | AOTNA00074 | |||
| 105821573 | PROCO11557 | |||
| 105858033 | MICMU13058 | |||
| 105998951 | DIPOR21978 |
