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Repository for lectin-assisted multimodality data
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MIRAGE
glutamate ionotropic receptor AMPA type subunit 1
Summary
- Gene Symbol
-
- GRIA1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Cell projection
- Disease variant
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Intellectual disability
- Ligand-gated ion channel
- Palmitate
- Phosphoprotein
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of receptor recycling | ||
| signal transduction | ||
| chemical synaptic transmission | ||
| synapse assembly | ||
| long-term memory |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum membrane | ||
| endoplasmic reticulum membrane | ||
| cytosol | ||
| plasma membrane | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| amyloid-beta binding | ||
| G-protein alpha-subunit binding | ||
| AMPA glutamate receptor activity | ||
| AMPA glutamate receptor activity | ||
| AMPA glutamate receptor activity |
GO Hierarchy
molecular function
transporter activity [inference]
binding [inference]
molecular transducer activity [inference]
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- glutamate
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ligand-gated monoatomic ion channel activity |
| monoatomic ion transport |
| InterPro |
|---|
| Periplasmic binding protein-like I |
| Receptor, ligand binding region |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060307 | autosomal dominant intellectual developmental disorder | |
| DOID:0081235 | autosomal recessive intellectual developmental disorder 76 | |
| DOID:1826 | epilepsy |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 2890 | Xenbase:XB-GENE-995621 | ||
| 2891 | FB:FBgn0264000 | ||
| 2892 | FB:FBgn0264000 | ||
| 2893 | FB:FBgn0264000 | ||
| 2897 | WB:WBGene00001612 | ||
| 2898 | WB:WBGene00001612 | ||
| 2899 | WB:WBGene00001612 | ||
| 14799 | Xenbase:XB-GENE-995621 | MOUSE05917 | |
| 14800 | FB:FBgn0264000 | ||
| 14802 | FB:FBgn0264000 |
