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Glutamate receptor 1

Summary

UniProt ID

P42261

Gene Symbol

GRIA1
GLUA1
GLUH1
GLUR1

Organism

Homo sapiens (human)

External Links

GlyGen: P42261
PubChem: P42261
The Human Metabolome Database: HMDBP02795
The O-GlcNAc Database: P42261
O-GlcNAcAtlas: P42261

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Cell projection
Disease variant
Disulfide bond
Endoplasmic reticulum
Endosome
Glycoprotein
Intellectual disability
Ligand-gated ion channel
Palmitate
Phosphoprotein
Postsynaptic cell membrane
Receptor
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

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GO Term
signal transduction
chemical synaptic transmission
synapse assembly
positive regulation of gene expression
neuronal action potential
spinal cord development
cerebral cortex development
response to estradiol
synaptic transmission, glutamatergic
modulation of chemical synaptic transmission

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GO Term
plasma membrane
cell-cell junction
neuromuscular junction
postsynaptic membrane
presynapse
dendrite
endocytic vesicle membrane
neuronal cell body
excitatory synapse
synaptic membrane

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GO Term
glutamate receptor activity
protein kinase binding
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
glutamate-gated calcium ion channel activity
PDZ domain binding
myosin V binding
G-protein beta-subunit binding
beta-2 adrenergic receptor binding
identical protein binding
amyloid-beta binding

Annotation information from UniProt.

Sequence

MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMPLGATGL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	GlyTouCan ID	Source
63	N-linked (GlcNAc...) asparagine		UniProt GlyGen
249	N-linked (GlcNAc...) asparagine		UniProt GlyGen
257	N-linked (GlcNAc...) asparagine		UniProt GlyGen
362		G27391WQ	GlyGen
363	N-linked (GlcNAc...) asparagine		UniProt GlyGen
401	N-linked (GlcNAc...) asparagine		UniProt GlyGen
406	N-linked (GlcNAc...) asparagine		UniProt GlyGen
849		G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 8** entries
Pathway Name	Organism
Activation of AMPA receptors	Homo sapiens
COPII-mediated vesicle transport	Homo sapiens
Cargo concentration in the ER	Homo sapiens
Long-term potentiation	Homo sapiens
Synaptic adhesion-like molecules	Homo sapiens
Trafficking of AMPA receptors	Homo sapiens
Trafficking of GluR2-containing AMPA receptors	Homo sapiens
Unblocking of NMDA receptors, glutamate binding and activation	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements