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Glutamate receptor 1

Summary

UniProt ID

P42261

Gene Symbol

GRIA1
GLUA1
GLUH1
GLUR1

Organism

Homo sapiens (human)

External Links

GlyGen: P42261
PubChem: P42261
The Human Metabolome Database: HMDBP02795
The O-GlcNAc Database: P42261
O-GlcNAcAtlas: P42261

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Cell projection
Disease variant
Disulfide bond
Endoplasmic reticulum
Endosome
Glycoprotein
Intellectual disability
Ligand-gated ion channel
Palmitate
Phosphoprotein
Postsynaptic cell membrane
Receptor
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

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GO Term
response to arsenic-containing substance
response to xenobiotic stimulus
regulation of receptor recycling
receptor internalization
long-term memory
signal transduction
chemical synaptic transmission
synapse assembly
positive regulation of gene expression
neuronal action potential

Displaying entries **1 - 10** of 31 in total

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GO Term
plasma membrane
cell-cell junction
neuromuscular junction
postsynaptic membrane
presynapse
dendrite
endocytic vesicle membrane
neuronal cell body
excitatory synapse
synaptic membrane

Displaying entries **11 - 20** of 20 in total

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GO Term
G-protein alpha-subunit binding
AMPA glutamate receptor activity
immunoglobulin binding
adenylate cyclase binding
small GTPase binding
glutamate receptor binding
protein kinase A binding
scaffold protein binding
ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

Annotation information from UniProt.

Sequence

MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMPLGATGL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	GlyTouCan ID	Source
63	N-linked (GlcNAc...) asparagine		UniProt GlyGen
249	N-linked (GlcNAc...) asparagine		UniProt GlyGen
257	N-linked (GlcNAc...) asparagine		UniProt GlyGen
362		G27391WQ	GlyGen
363	N-linked (GlcNAc...) asparagine		UniProt GlyGen
401	N-linked (GlcNAc...) asparagine		UniProt GlyGen
406	N-linked (GlcNAc...) asparagine		UniProt GlyGen
849		G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 8** entries
Pathway Name	Organism
Activation of AMPA receptors	Homo sapiens
COPII-mediated vesicle transport	Homo sapiens
Cargo concentration in the ER	Homo sapiens
Long-term potentiation	Homo sapiens
Synaptic adhesion-like molecules	Homo sapiens
Trafficking of AMPA receptors	Homo sapiens
Trafficking of GluR2-containing AMPA receptors	Homo sapiens
Unblocking of NMDA receptors, glutamate binding and activation	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements