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IFI30, lysosomal thiol reductase

Summary

Gene Symbol

Ifi30

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

290644

PubChem

290644

Alliance of Genome Resources

RGD:1310758

Annotation

Keyword

Disulfide bond
Glycoprotein
Immunity
Lysosome
Oxidoreductase
Redox-active center
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q499T2	Interferon gamma inducible protein 30

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
immune system process	IEA
antigen processing and presentation of exogenous peptide antigen via MHC class II	ISO
antigen processing and presentation of exogenous peptide antigen via MHC class I	ISS
antigen processing and presentation of exogenous peptide antigen via MHC class I	ISO
negative regulation of fibroblast proliferation	ISO

GO Hierarchy

biological process

immune system process

antigen processing and presentation [inference]

antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [inference]

antigen processing and presentation of peptide antigen via MHC class II [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class II

antigen processing and presentation of exogenous antigen [inference]

antigen processing and presentation of exogenous peptide antigen [inference]

antigen processing and presentation of peptide antigen [inference]

antigen processing and presentation of peptide antigen via MHC class I [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class I

antigen processing and presentation of exogenous peptide antigen [inference]

antigen processing and presentation of peptide antigen via MHC class II [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class II

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of fibroblast proliferation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of fibroblast proliferation

regulation of fibroblast proliferation [inference]

negative regulation of fibroblast proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of fibroblast proliferation

regulation of biological quality [inference]

regulation of protein stability [inference]

protein stabilization

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GO Term	Evidence Code	PMID
extracellular region	IEA
lysosome	ISS
lysosome	ISO
lysosome	IBA
lysosome	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 4** entries
GO Term	Evidence Code	PMID
oxidoreductase activity, acting on a sulfur group of donors	ISS
oxidoreductase activity, acting on a sulfur group of donors	ISO
oxidoreductase activity, acting on a sulfur group of donors	IBA
oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on a sulfur group of donors

oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

gamma-interferon-inducible lysosomal thiol reductase

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
immune system process
oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
oxidoreductase activity, acting on a sulfur group of donors
oxidoreductase activity

Displaying 1 entry
InterPro
Gamma interferon inducible lysosomal thiol reductase GILT

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	10437	Xenbase:XB-GENE-1002315	HUMAN41906
Danio rerio	41650	ZFIN:ZDB-GENE-030131-8447
Danio rerio	42788	ZFIN:ZDB-GENE-131127-557
Mus musculus	65972	Xenbase:XB-GENE-1002315	MOUSE60500
Xenopus tropicalis	176203	Xenbase:XB-GENE-1002315
Danio rerio	191388	ZFIN:ZDB-GENE-030131-8447
Xenopus tropicalis	290644	Xenbase:XB-GENE-1002315
Danio rerio	336503	Xenbase:XB-GENE-1002315	DANRE49135
Canis lupus familiaris	476669		CANLF07651
Macaca mulatta	719379		MACMU19455