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C-X-C motif chemokine receptor 5

Summary

Gene Symbol

Cxcr5

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

29363

PubChem

29363

Alliance of Genome Resources

RGD:62010

Annotation

Keyword

B-cell activation
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A6J404
G3V7M1
P34997	Burkitt lymphoma receptor 1 homolog Neurolymphatic receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
lymph node development	IEA ISO
B cell activation	IEA
calcium-mediated signaling	IBA
cell chemotaxis	IBA
chemokine-mediated signaling pathway	IEA

GO Hierarchy

biological process

immune system process [inference]

immune response

leukocyte activation [inference]

lymphocyte activation [inference]

B cell activation

leukocyte migration [inference]

leukocyte chemotaxis

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

B cell activation

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

chemokine-mediated signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

leukocyte chemotaxis

cell chemotaxis

leukocyte chemotaxis

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

B cell activation

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

hematopoietic or lymphoid organ development [inference]

lymph node development

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

leukocyte chemotaxis

response to stimulus [inference]

immune response

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

positive regulation of cell division [inference]

positive regulation of cytokinesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

chemokine-mediated signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

positive regulation of cell division [inference]

positive regulation of cytokinesis

regulation of cell division [inference]

regulation of cytokinesis [inference]

positive regulation of cytokinesis

positive regulation of cell division [inference]

positive regulation of cytokinesis

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of cytokinesis [inference]

positive regulation of cytokinesis

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying 1 entry
GO Term	Evidence Code	PMID
external side of plasma membrane	IBA IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

side of membrane [inference]

external side of plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
C-X-C chemokine receptor activity	IEA
C-C chemokine receptor activity	IBA
C-C chemokine binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytokine binding [inference]

chemokine binding [inference]

C-C chemokine binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity [inference]

chemokine receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled chemoattractant receptor activity [inference]

chemokine receptor activity [inference]

immune receptor activity [inference]

cytokine receptor activity [inference]

chemokine receptor activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

C-X-C chemokine receptor type 5

Functional Category

B: Chromatin structure and dynamics
J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying entries **1 - 10** of 11 in total

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Gene Ontology
B cell activation
C-C chemokine binding
C-C chemokine receptor activity
C-X-C chemokine receptor activity
calcium-mediated signaling
cell chemotaxis
chemokine-mediated signaling pathway
chemotaxis
immune response
lymph node development

Displaying **all 3** entries
InterPro
CXC chemokine receptor 5
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

Displaying entries **31 - 40** of **117** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Heterocephalus glaber	101724362	10181_0:002a20		HETGA04280
Mesocricetus auratus	101833055	10036_0:0037d2
Chrysemys picta bellii	101945857			CHRPI10187
Ictidomys tridecemlineatus	101961917	43179_0:0014b6		ICTTR09568
Microtus ochrogaster	101993494	79684_0:000d7d
Chinchilla lanigera	102020318	34839_0:000a2d		CHILA03444
Capra hircus	102170801			CAPHI06125
Haplochromis burtoni	102310687			HAPBU20303
Latimeria chalumnae	102354653			LATCH18934
Neolamprologus brichardi	102783324			NEOBR16631

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024