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C-X-C motif chemokine receptor 5

Summary

Gene Symbol

Cxcr5

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

29363

PubChem

29363

Alliance of Genome Resources

RGD:62010

Annotation

Keyword

B-cell activation
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A6J404
G3V7M1
P34997	Burkitt lymphoma receptor 1 homolog Neurolymphatic receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
lymph node development	IEA ISO
B cell activation	IEA
calcium-mediated signaling	IBA
cell chemotaxis	IBA
chemokine-mediated signaling pathway	IEA

GO Hierarchy

biological process

immune system process [inference]

immune response

leukocyte activation [inference]

lymphocyte activation [inference]

B cell activation

leukocyte migration [inference]

leukocyte chemotaxis

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

B cell activation

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

chemokine-mediated signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

leukocyte chemotaxis

cell chemotaxis

leukocyte chemotaxis

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

B cell activation

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

hematopoietic or lymphoid organ development [inference]

lymph node development

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

leukocyte chemotaxis

response to stimulus [inference]

immune response

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

positive regulation of cell division [inference]

positive regulation of cytokinesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

chemokine-mediated signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

positive regulation of cell division [inference]

positive regulation of cytokinesis

regulation of cell division [inference]

regulation of cytokinesis [inference]

positive regulation of cytokinesis

positive regulation of cell division [inference]

positive regulation of cytokinesis

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of cytokinesis [inference]

positive regulation of cytokinesis

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying 1 entry
GO Term	Evidence Code	PMID
external side of plasma membrane	IBA IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

side of membrane [inference]

external side of plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
C-X-C chemokine receptor activity	IEA
C-C chemokine receptor activity	IBA
C-C chemokine binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytokine binding [inference]

chemokine binding [inference]

C-C chemokine binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity [inference]

chemokine receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled chemoattractant receptor activity [inference]

chemokine receptor activity [inference]

immune receptor activity [inference]

cytokine receptor activity [inference]

chemokine receptor activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

C-X-C chemokine receptor type 5

Functional Category

B: Chromatin structure and dynamics
J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying entries **1 - 10** of 11 in total

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Gene Ontology
B cell activation
C-C chemokine binding
C-C chemokine receptor activity
C-X-C chemokine receptor activity
calcium-mediated signaling
cell chemotaxis
chemokine-mediated signaling pathway
chemotaxis
immune response
lymph node development

Displaying **all 3** entries
InterPro
CXC chemokine receptor 5
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

Displaying entries **41 - 50** of **117** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Peromyscus maniculatus bairdii	102915741	230844_0:00242f
Astyanax mexicanus	103046415			ASTMX11285
Erinaceus europaeus	103114010			ERIEU05200
Poecilia formosa	103138208			POEFO06220
Callorhinchus milii	103190425			CALMI43680
Chlorocebus sabaeus	103248608			CHLSB01069
Carlito syrichta	103272049			CARSF17987
Poecilia reticulata	103475052			POERE06932
Nannospalax galili	103727932	1026970_0:005064		NANGA06560
Serinus canaria	103822775			SERCA19598

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024