GlyCosmos Portal

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GO Term	Evidence Code	PMID
protein binding	IPI	10856833 11005803 11801590 14657349 16403449 19377479 25241761 26300262 26496610 33961781 34591612 35271311 8942985 9774676
ATP binding	IDA	15105434
ATP-dependent activity, acting on DNA	IDA	16403449
enzyme binding	IPI	26300262
mismatched DNA binding	IDA	11756455 11801590 23622243 8942985

GO Hierarchy

molecular function

catalytic activity [inference]

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

ATP-dependent activity, acting on DNA

ATP-dependent DNA damage sensor activity

binding [inference]

protein binding

enzyme binding

histone binding [inference]

methylated histone binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

modification-dependent protein binding [inference]

methylation-dependent protein binding [inference]

methylated histone binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

ADP binding

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

protein-containing complex binding [inference]

chromatin binding

mismatch repair complex binding [inference]

MutLalpha complex binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

DNA secondary structure binding [inference]

four-way junction DNA binding

damaged DNA binding

oxidized DNA binding [inference]

oxidized purine DNA binding

double-stranded DNA binding

mismatched DNA binding

DNA insertion or deletion binding [inference]

single base insertion or deletion binding [inference]

guanine/thymine mispair binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

small molecule sensor activity [inference]

DNA damage sensor activity [inference]

ATP-dependent DNA damage sensor activity

ATP-dependent activity [inference]

ATP-dependent activity, acting on DNA

ATP-dependent DNA damage sensor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

DNA mismatch repair

Functional Category

K: Transcription
L: Replication, recombination and repair
T: Signal transduction mechanisms
V: Defense mechanisms

Displaying **all 4** entries
Gene Ontology
ATP binding
ATP-dependent DNA damage sensor activity
DNA repair
nucleotide binding

Displaying entries **1 - 10** of 11 in total

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InterPro
DNA mismatch repair MutS family
DNA mismatch repair protein MutS, C-terminal
DNA mismatch repair protein MutS, N-terminal
DNA mismatch repair protein MutS, clamp
DNA mismatch repair protein MutS, connector domain
DNA mismatch repair protein MutS, core domain superfamily
DNA mismatch repair protein MutS, core
DNA mismatch repair protein MutS-like, N-terminal
DNA mismatch repair protein MutS/MSH
MutS, connector domain superfamily

Disease

Disease Ontology

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:0070272	hereditary nonpolyposis colorectal cancer type 5	Alliance of Genome Resources
DOID:0080199	colorectal carcinoma	Alliance of Genome Resources
DOID:0112182	mismatch repair cancer syndrome	Alliance of Genome Resources
DOID:1380	endometrial cancer	Alliance of Genome Resources
DOID:3883	Lynch syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 85 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	2956	Xenbase:XB-GENE-986638
Mus musculus	17688	Xenbase:XB-GENE-986638	MOUSE19802
Danio rerio	260437		DANRE06027
Pan troglodytes	459218		PANTR27568
Canis lupus familiaris	474585		CANLF01822
Bos taurus	540526		BOVIN02354
Macaca mulatta	715701		MACMU08095
Equus caballus	100068065		HORSE10549
Ciona intestinalis	100185806		CIOIN06460
Taeniopygia guttata	100227810		TAEGU22070

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements