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nicalin

Summary

Gene Symbol

Ncln

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

314648

PubChem

314648

Alliance of Genome Resources

RGD:1309355

Annotation

Keyword

Endoplasmic reticulum
Glycoprotein
Proteomics identification
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A6K875
Q5XIA1	Nicalin Nicastrin-like protein
A0A0H2UHD9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein stabilization	IEA ISO
multi-pass transmembrane protein insertion into ER membrane	IEA ISO ISS
regulation of protein complex stability	IEA ISO
regulation of protein-containing complex assembly	IEA ISO
regulation of signal transduction	IBA IEA

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

establishment of localization [inference]

establishment of protein localization [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly

regulation of cellular component organization [inference]

regulation of protein-containing complex assembly

regulation of biological quality [inference]

regulation of protein stability [inference]

protein stabilization

regulation of protein complex stability

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane	IEA
protein-containing complex	ISO
endoplasmic reticulum membrane	IBA IEA ISO
multi-pass translocon complex	IEA ISO ISS
endoplasmic reticulum	IEA

GO Hierarchy

cellular component

protein-containing complex

ER membrane insertion complex [inference]

multi-pass translocon complex

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying 1 entry
GO Term	Evidence Code	PMID
ribosome binding	IEA ISO ISS

GO Hierarchy

molecular function

binding [inference]

protein-containing complex binding [inference]

ribonucleoprotein complex binding [inference]

ribosome binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

BOS complex subunit NCLN

Functional Category

O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Nicalin
Peptidase M28

Ortholog

Displaying entries **1 - 10** of **104** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	34388		FB:FBgn0032217
Homo sapiens	56926		HGNC:26923	HUMAN39707
Mus musculus	103425	10090_1:003363	MGI:1926081	MOUSE02975
Caenorhabditis elegans	172803		WB:WBGene00011488
Danio rerio	336844		ZFIN:ZDB-GENE-030131-8788	DANRE22965
Pan troglodytes	468663			PANTR16756
Canis lupus familiaris	485062			CANLF08046
Bos taurus	531802			BOVIN32949
Xenopus tropicalis	595051		Xenbase:XB-GENE-1004030
Monodelphis domestica	100010200			MONDO18286