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MIRAGE
heterogeneous nuclear ribonucleoprotein A1
Summary
- Gene Symbol
-
- HNRNPA1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Amyotrophic lateral sclerosis
- Cytoplasm
- Direct protein sequencing
- Disease variant
- Host-virus interaction
- Isopeptide bond
- Methylation
- Nucleus
- Phosphoprotein
- Proteomics identification
- RNA-binding
- Reference proteome
- Repeat
- Ribonucleoprotein
- Spliceosome
- Ubl conjugation
- mRNA transport
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A024RB53 |
|
| P09651 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of alternative mRNA splicing, via spliceosome | ||
| mRNA splicing, via spliceosome | ||
| mRNA splicing, via spliceosome | ||
| RNA export from nucleus | ||
| negative regulation of telomere maintenance via telomerase |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA binding | ||
| single-stranded DNA binding | ||
| RNA binding | ||
| single-stranded RNA binding | ||
| mRNA 3'-UTR binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Heterogeneous nuclear ribonucleoprotein
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- K: Transcription
- T: Signal transduction mechanisms
| InterPro |
|---|
| Nucleotide-binding alpha-beta plait domain superfamily |
| RNA recognition motif domain |
| RNA-binding domain superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060211 | amyotrophic lateral sclerosis type 20 | |
| DOID:0111189 | distal myopathy 3 | |
| DOID:0111386 | inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 3 | |
| DOID:321 | HTLV-1-associated myelopathy/tropical spastic paraparesis |
