HTLV-1-associated myelopathy/tropical spastic paraparesis

Summary
Synonym
  • HAM/TSP
  • HTLV-associated myelopathy
  • Tropical spastic paralysis
  • Tropical spastic paraplegia
  • tropical spastic paraparesis
Definition
A viral infectious disease that results in inflammation located in spinal cord, has_material_basis_in human T-cell leukemia virus type 1 (Deltaretrovirus priTlym1), which is transmitted by sexual contact, and transmitted by breast feeding. The infection has symptom spastic weakness of both legs, has symptom muscle stiffness, has symptom sensory disturbance, and has symptom spasms.
Super Class
spinal cord disease viral infectious disease
Disease Ontology
DOID:321
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
Related Genes
Displaying all 4 entries
Gene ID Gene Symbol Description Source
3119 HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
3178 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
4790 NFKB1 nuclear factor kappa B subunit 1
22914 KLRK1 killer cell lectin like receptor K1

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025