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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
NKG2-D type II integral membrane protein
Summary
- UniProt ID
- P26718
- Gene Symbol
-
- KLRK1
- D12S2489E
- NKG2D
- Organism
- Homo sapiens (human)
External Links
- PubChem
- P26718
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Alternative splicing
- Cell membrane
- Differentiation
- Disulfide bond
- Glycoprotein
- Innate immunity
- Lectin
- Receptor
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| external side of plasma membrane |
| cell surface |
| plasma membrane |
| membrane |
| GO Term |
|---|
| MHC class Ib receptor activity |
| signaling receptor activity |
| carbohydrate binding |
| MHC class I protein binding |
| identical protein binding |
Sequence
MGWIRGRRSRHSWEMSEFHNYNLDLKKSDFSTRWQKQRCPVVKSKCRENASPFFFCCFIAVAMGIRFIIMVTIWSAVFLNSLFNQEVQIPLTESYCGPCPKNWICYKNNCYQFFDESKNWYESQASCMSQNASLLKVYSKEDQDLLKLVKSYHWMGLVHIPTNGSWQWEDGSILSPNLLTIIEMQKGDCALYASSFKGYIENCSTPNTYICMQRTV
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| DAP12 interactions | Homo sapiens |
| DAP12 signaling | Homo sapiens |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050156 | idiopathic pulmonary fibrosis | |
| DOID:0050424 | familial adenomatous polyposis | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050646 | distal arthrogryposis | |
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:0060058 | lymphoma | |
| DOID:0060060 | non-Hodgkin lymphoma | |
| DOID:0060192 | Crohn's colitis | |
| DOID:0060262 | gallbladder disease | |
| DOID:0060284 | paroxysmal nocturnal hemoglobinuria |
