DAP12 signaling

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
FYN,LCKDAP12 receptors:p-Y91,Y102-DAP12 dimerATPADPDAP12 receptors:DAP12 dimerSYKDAP12 receptors:p-DAP12:SYKDAP12 Receptors:p-DAP12:p-6Y-SYKDAP12 Receptors:p-DAP12:p-6Y-SYK:PI3KPI3KPIP2PIP3LAT-2p-5Y-LAT-2p-5Y-LAT:p-SHC1:GRB2:SOS1p-SHC1:GRB2:SOSp-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76GADS:SLP76PLC gamma1,2p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76:PLCGGTPp21 RAS:GTPGDPp21 RAS:GDPp-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCGp-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3VAV2,VAV3BTKp-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTKp-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV:p-PLCGp-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAVp-4Y-PLCGp-5Y-LAT:PLCG1:GADS:p-3Y-SLP-76:BTK:p-VAVRAC1:GDPRAC1:GTP
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 3 entries
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_000802 Q13241 Natural killer cells antigen CD94 view
GL_000820 P26717 NKG2-C type II integral membrane protein view
GL_000823 P26718 NKG2-D type II integral membrane protein view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025